XML 107 R95.htm IDEA: XBRL DOCUMENT v3.22.0.1
Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) - USD ($)
$ in Millions
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Deferred tax assets:      
Net operating loss carryforwards $ 413 $ 587  
Stock-based compensation 117 113  
Reserves and accruals not currently deductible 700 444  
Excess of tax basis over book basis of intangible assets 1,157 1,177  
Upfront and milestone payments 1,310 1,144  
Research and other credit carryforwards 249 219  
Equity investments 117 116  
Liability related to future royalties 274 247  
Other, net 292 311  
Total deferred tax assets before valuation allowance 4,629 4,358  
Valuation allowance (520) (398) $ (217)
Total deferred tax assets 4,109 3,960  
Deferred tax liabilities:      
Property, plant and equipment (227) (202)  
Excess of book basis over tax basis of intangible assets (6,719) (6,168)  
Other (180) (202)  
Total deferred tax liabilities (7,126) (6,572)  
Net deferred tax assets (liabilities) $ (3,017) $ (2,612)