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REVENUES (Tables)
3 Months Ended
Mar. 31, 2022
Revenue from Contract with Customer [Abstract]  
Disaggregation of Revenues
The following table summarizes our Total revenues:
Three Months Ended March 31, 2022Three Months Ended March 31, 2021
(in millions)U.S.EuropeOther InternationalTotalU.S.EuropeOther InternationalTotal
Product sales:
HIV
Biktarvy$1,706 $261 $184 $2,151 $1,465 $216 $143 $1,824 
Complera/Eviplera17 24 44 25 34 63 
Descovy311 32 31 374 282 42 35 359 
Genvoya457 77 48 582 506 106 61 673 
Odefsey232 96 11 339 240 113 14 367 
Stribild22 32 31 11 46 
Truvada28 38 119 135 
Revenue share - Symtuza(1)
86 44 132 89 44 135 
Other HIV(2)
14 29 14 48 
Total HIV2,862 550 295 3,707 2,786 578 286 3,650 
Veklury801 304 430 1,535 820 388 248 1,456 
Hepatitis C virus (“HCV”)
Ledipasvir/Sofosbuvir(3)
13 18 35 19 16 21 56 
Sofosbuvir/Velpatasvir(4)
162 83 85 330 214 75 92 381 
Other HCV(5)
24 34 25 44 73 
Total HCV199 95 105 399 258 135 117 510 
Hepatitis B virus (“HBV”) / Hepatitis delta virus (“HDV”)
Vemlidy80 111 200 77 96 181 
Viread— 17 23 20 31 
Other HBV/HDV(6)
— 13 — 13 — — 
Total HBV/HDV80 28 128 235 81 23 116 220 
Cell therapy
Tecartus47 15 63 27 — 31 
Yescarta125 77 211 92 61 160 
Total cell therapy172 92 10 274 119 65 191 
Trodelvy119 25 146 72 — — 72 
Other
AmBisome25 66 53 144 12 66 43 121 
Letairis43 — — 43 54 — — 54 
Other(7)
26 15 50 38 20 66 
Total other94 81 62 236 104 86 51 241 
Total product sales4,329 1,174 1,031 6,534 4,240 1,275 825 6,340 
Royalty, contract and other revenues27 27 56 20 61 83 
Total revenues$4,355 $1,202 $1,033 $6,590 $4,260 $1,336 $827 $6,423 
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(1)     Represents our revenue from cobicistat (“C”), emtricitabine (“FTC”) and tenofovir alafenamide (“TAF”) in Symtuza (darunavir/C/FTC/TAF), a fixed dose combination product commercialized by Janssen Sciences Ireland Unlimited Company (“Janssen”).
(2)     Includes Atripla, Emtriva and Tybost.
(3)     Amounts consist of sales of Harvoni and the authorized generic version of Harvoni sold by our separate subsidiary, Asegua Therapeutics LLC.
(4)     Amounts consist of sales of Epclusa and the authorized generic version of Epclusa sold by our separate subsidiary, Asegua Therapeutics LLC.
(5)     Includes Vosevi and Sovaldi.
(6)     Includes Hepcludex and Hepsera.
(7)     Includes Cayston, Jyseleca, Ranexa and Zydelig.
Revenues from Major Customers
The following table summarizes revenues from each of our customers who individually accounted for 10% or more of our total revenues:
Three Months Ended
 March 31,
(as a percentage of total revenues)20222021
AmerisourceBergen Corporation19 %27 %
Cardinal Health, Inc.23 %18 %
McKesson Corporation20 %17 %
Revenues Recognized from Performance Obligations Satisfied in Prior Periods
The following table summarizes revenues recognized from performance obligations satisfied in prior periods:
Three Months Ended
March 31,
(in millions)20222021
Revenue share with Janssen and royalties for licenses of intellectual property$184 $226 
Changes in estimates$230 $332