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AVAILABLE-FOR-SALE DEBT SECURITIES AND EQUITY SECURITIES (Tables)
9 Months Ended
Sep. 30, 2022
Debt Securities, Available-for-Sale [Abstract]  
Reconciliation of Available-for-Sale Debt Securities from Cost Basis to Fair Value
The following table summarizes our available-for-sale debt securities:
September 30, 2022December 31, 2021
(in millions)Amortized CostGross Unrealized GainsGross Unrealized LossesEstimated Fair Value Amortized CostGross Unrealized GainsGross Unrealized LossesEstimated Fair Value 
U.S. treasury securities$456 $— $(7)$448 $408 $— $(1)$407 
U.S. government agencies securities19 — — 19 — — 
Non-U.S. government securities44 — — 44 50 — — 50 
Certificates of deposit65 — — 65 249 — — 249 
Corporate debt securities1,397 — (30)1,367 1,365 — (2)1,363 
Residential mortgage and asset-backed securities350 — (3)347 425 — (1)424 
Total$2,331 $— $(40)$2,290 $2,501 $— $(4)$2,497 
Summary of Classification of Available-for-Sale Debt Securities
The following table summarizes the classification of our available-for-sale debt securities in our Condensed Consolidated Balance Sheets:
(in millions)September 30, 2022December 31, 2021
Cash and cash equivalents$47 $
Short-term marketable debt securities961 1,182 
Long-term marketable debt securities1,282 1,309 
Total$2,290 $2,497 
Summary of Available-for-Sale Debt Securities by Contractual Maturity
The following table summarizes our available-for-sale debt securities by contractual maturity:
September 30, 2022
(in millions)Amortized CostFair Value
Within one year$1,018 $1,008 
After one year through five years1,298 1,268 
After five years through ten years
After ten years
Total$2,331 $2,290 
Summary of Equity Securities
The following table summarizes the classification of our equity securities measured at fair value on a recurring basis on our Condensed Consolidated Balance Sheets. Prepaid and other current assets and Other long-term assets include our equity method investments in Arcus and Galapagos, respectively, for which we elected and applied the fair value option as we believe it best reflects the underlying economics of these investments.
(in millions)September 30, 2022December 31, 2021
Cash and cash equivalents$3,316 $3,661 
Prepaid and other current assets578 885 
Other long-term assets899 1,197 
Total$4,793 $5,743