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Goodwill and Intangible Assets (Tables)
12 Months Ended
Dec. 31, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill
The following table summarizes the changes in the carrying amount of Goodwill:
December 31,
(in millions)20222021
Beginning balance
$8,332 $8,108 
Goodwill resulting from acquisitions— 226 
Measurement period adjustments(18)(2)
Ending balance$8,314 $8,332 
Indefinite-Lived Intangible Assets
The following table summarizes our Intangible assets, net:
 December 31, 2022December 31, 2021
(in millions)Gross 
Carrying
Amount
Accumulated
Amortization
Foreign Currency Translation AdjustmentNet Carrying AmountGross 
Carrying
Amount
Accumulated
Amortization
Foreign Currency Translation AdjustmentNet Carrying Amount
Finite-lived assets:
Intangible asset – sofosbuvir$10,720 $(6,350)$— $4,370 $10,720 $(5,651)$— $5,069 
Intangible asset – axicabtagene ciloleucel
7,110 (1,908)— 5,202 7,110 (1,501)— 5,609 
Intangible asset – Trodelvy5,630 (973)— 4,657 5,630 (507)— 5,123 
Intangible asset – Hepcludex
845 (158)— 687 845 (72)— 773 
Other1,489 (733)758 1,610 (650)961 
Total finite-lived assets25,794 (10,121)15,674 25,915 (8,381)17,535 
Indefinite-lived assets – IPR&D(1)
13,220 — — 13,220 15,920 — — 15,920 
Total intangible assets$39,014 $(10,121)$$28,894 $41,835 $(8,381)$$33,455 
_______________________________
(1)    In February 2023, FDA granted approval of Trodelvy for use in adult patients with unresectable locally advanced or metastatic HR+/HER2- breast cancer who have received endocrine-based therapy and at least two additional systemic therapies in the metastatic setting. Accordingly, the related IPR&D intangible asset of $6.1 billion will be reclassified to finite-lived assets in the first quarter of 2023.
Finite-Lived Intangible Assets
The following table summarizes our Intangible assets, net:
 December 31, 2022December 31, 2021
(in millions)Gross 
Carrying
Amount
Accumulated
Amortization
Foreign Currency Translation AdjustmentNet Carrying AmountGross 
Carrying
Amount
Accumulated
Amortization
Foreign Currency Translation AdjustmentNet Carrying Amount
Finite-lived assets:
Intangible asset – sofosbuvir$10,720 $(6,350)$— $4,370 $10,720 $(5,651)$— $5,069 
Intangible asset – axicabtagene ciloleucel
7,110 (1,908)— 5,202 7,110 (1,501)— 5,609 
Intangible asset – Trodelvy5,630 (973)— 4,657 5,630 (507)— 5,123 
Intangible asset – Hepcludex
845 (158)— 687 845 (72)— 773 
Other1,489 (733)758 1,610 (650)961 
Total finite-lived assets25,794 (10,121)15,674 25,915 (8,381)17,535 
Indefinite-lived assets – IPR&D(1)
13,220 — — 13,220 15,920 — — 15,920 
Total intangible assets$39,014 $(10,121)$$28,894 $41,835 $(8,381)$$33,455 
Estimated Future Amortization Expense of Finite-Lived Intangible Assets
The following table summarizes the estimated future amortization expense associated with our finite-lived intangible assets as of December 31, 2022:
(in millions)Amount
2023$1,777 
20241,777 
20251,771 
20261,763 
20271,763 
Thereafter6,824 
Total$15,674