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Debt and Credit Facilities - Summary of Debt Carrying Amount (Details) - USD ($) $ in Millions	Dec. 31, 2022	Dec. 31, 2021
Debt Instrument [Line Items]
Total debt, net	$ 25,229	$ 26,695
Less: Current portion of long-term debt and other obligations, net	2,273	1,516
Total Long-term debt, net	22,957	25,179
Senior notes
Debt Instrument [Line Items]
Total debt, net	$ 24,250
Senior notes | 1.95% Senior Unsecured Notes Due in March 2022
Debt Instrument [Line Items]
Interest Rate	1.95%
Total debt, net	$ 0	500
Senior notes | 3.25% Senior Unsecured Notes Due in September 2022
Debt Instrument [Line Items]
Interest Rate	3.25%
Total debt, net	$ 0	999
Senior notes | 2.50% Senior Unsecured Notes Due in September 2023
Debt Instrument [Line Items]
Interest Rate	2.50%
Total debt, net	$ 749	748
Senior notes | 0.75% Senior Unsecured Notes Due in September 2023
Debt Instrument [Line Items]
Interest Rate	0.75%
Total debt, net	$ 1,498	1,496
Senior notes | 3.70% Senior Unsecured Notes Due in April 2024
Debt Instrument [Line Items]
Interest Rate	3.70%
Total debt, net	$ 1,748	1,747
Senior notes | 3.50% Senior Unsecured Notes Due in February 2025
Debt Instrument [Line Items]
Interest Rate	3.50%
Total debt, net	$ 1,748	1,747
Senior notes | 3.65% Senior Unsecured Notes Due in March 2026
Debt Instrument [Line Items]
Interest Rate	3.65%
Total debt, net	$ 2,742	2,739
Senior notes | 2.95% Senior Unsecured Notes Due in March 2027
Debt Instrument [Line Items]
Interest Rate	2.95%
Total debt, net	$ 1,247	1,247
Senior notes | 1.20% Senior Unsecured Notes Due October 2027
Debt Instrument [Line Items]
Interest Rate	1.20%
Total debt, net	$ 747	746
Senior notes | 1.65% Senior Unsecured Notes Due October 2030
Debt Instrument [Line Items]
Interest Rate	1.65%
Total debt, net	$ 993	993
Senior notes | 4.60% Senior Unsecured Notes Due in September 2035
Debt Instrument [Line Items]
Interest Rate	4.60%
Total debt, net	$ 993	992
Senior notes | 4.00% Senior Unsecured Notes Due in September 2036
Debt Instrument [Line Items]
Interest Rate	4.00%
Total debt, net	$ 742	742
Senior notes | 2.60% Senior Unsecured Notes Due October 2040
Debt Instrument [Line Items]
Interest Rate	2.60%
Total debt, net	$ 988	987
Senior notes | 5.65% Senior Unsecured Notes Due in December 2041
Debt Instrument [Line Items]
Interest Rate	5.65%
Total debt, net	$ 996	996
Senior notes | 4.80% Senior Unsecured Notes Due in April 2044
Debt Instrument [Line Items]
Interest Rate	4.80%
Total debt, net	$ 1,736	1,736
Senior notes | 4.50% Senior Unsecured Notes Due in February 2045
Debt Instrument [Line Items]
Interest Rate	4.50%
Total debt, net	$ 1,733	1,733
Senior notes | 4.75% Senior Unsecured Notes Due in March 2046
Debt Instrument [Line Items]
Interest Rate	4.75%
Total debt, net	$ 2,221	2,220
Senior notes | 4.15% Senior Unsecured Notes Due in March 2047
Debt Instrument [Line Items]
Interest Rate	4.15%
Total debt, net	$ 1,728	1,727
Senior notes | 2.80% Senior Unsecured Notes Due October 2050
Debt Instrument [Line Items]
Interest Rate	2.80%
Total debt, net	$ 1,477	1,476
Senior Notes and Medium-Term Notes
Debt Instrument [Line Items]
Total senior unsecured notes	24,088	25,571
Liability related to future royalties
Debt Instrument [Line Items]
Total debt, net	$ 1,141	$ 1,124

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