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PROPERTY, PLANT AND EQUIPMENT | 12 Months Ended
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Dec. 31, 2023
Property, Plant and Equipment [Abstract] |
PROPERTY, PLANT AND EQUIPMENT | PROPERTY, PLANT AND EQUIPMENT The following table summarizes our Property, plant and equipment, net by asset type:
|  | December 31,
(in millions) |  | 2023 |  | 2022
Land and land improvements |  | $ | 561 |  |  | $ | 562 |
Buildings and improvements (including leasehold improvements) |  | 4,328 |  |  | 4,390 |
Laboratory and manufacturing equipment |  | 1,147 |  |  | 1,110 |
Office, computer equipment and other |  | 1,069 |  |  | 880 |
Construction in progress |  | 661 |  |  | 719 |
Subtotal |  | 7,766 |  |  | 7,661 |
Less: accumulated depreciation |  | 2,449 |  |  | 2,186 |
Total |  | $ | 5,317 |  |  | $ | 5,475 |
In 2023, we wrote off $381 million of property, plant and equipment related to changes in our manufacturing strategy. The write-offs related primarily to buildings, improvements and related equipment that were determined to be fully impaired based on the difference between fair value and the carrying amount as a result of our decision to no longer utilize the facilities. The following table summarizes our Property, plant and equipment, net by geography:
|  | December 31,
(in millions) |  | 2023 |  | 2022
U.S. |  | $ | 4,691 |  |  | 4,501 |
International(1) |  | 626 |  |  | 973 |
Total |  | $ | 5,317 |  |  | $ | 5,475 |
________________________________ (1) All individual international locations accounted for less than 10% of the total balances.

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- Definition The entire disclosure for long-lived, physical asset used in normal conduct of business and not intended for resale. Includes, but is not limited to, work of art, historical treasure, and similar asset classified as collections. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -Name Accounting Standards Codification -Publisher FASB -URI https://asc.fasb.org//360/tableOfContent Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 6 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-6 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (d) -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-1 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Name Accounting Standards Codification -Section 50 -Paragraph 7 -SubTopic 360 -Topic 958 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480321/958-360-50-7 + Details
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