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EMPLOYEE BENEFITS - Summary of Stock-Based Compensation (Details) - USD ($) $ in Millions | 12 Months Ended
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Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | $ 796 | $ 645 | $ 635
Income tax effect | (165) | (91) | (100)
Stock-based compensation expense, net of tax | 630 | 553 | 535
Acquisition-related expense |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 29 | 8 | 0
Acquisition-related expense | XinThera, Inc |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 19 |  |
Acquisition-related expense | Tmunity Therapeutics |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 10 |  |
Acquisition-related expense | MiroBio Ltd. |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses |  | 8 |
Cost of goods sold |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 57 | 46 | 40
Research and development expenses |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 377 | 285 | 287
Selling, general and administrative expenses |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 361 | 313 | 308
RSUs |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 666 | 557 | 558
PSUs |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 32 | 25 | 17
Stock options |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | 30 | 28 | 29
ESPP |  |  |
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] |  |  |
Stock-based compensation expense included in total costs and expenses | $ 37 | $ 26 | $ 31

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