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PROPERTY, PLANT AND EQUIPMENT (Tables) | 12 Months Ended
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Dec. 31, 2024
Property, Plant and Equipment [Abstract] |
Summary of Property, Plant and Equipment | The following table summarizes our Property, plant and equipment, net by asset type:
|  | December 31,
(in millions) |  | 2024 |  | 2023
Land and land improvements |  | $ | 561 |  |  | $ | 561 |
Buildings and improvements (including leasehold improvements) |  | 4,539 |  |  | 4,328 |
Laboratory and manufacturing equipment |  | 1,192 |  |  | 1,147 |
Office, computer equipment and other |  | 1,090 |  |  | 1,069 |
Construction in progress |  | 501 |  |  | 661 |
Subtotal |  | 7,884 |  |  | 7,766 |
Less: accumulated depreciation |  | 2,470 |  |  | 2,449 |
Total |  | $ | 5,414 |  |  | $ | 5,317 |
The following table summarizes our Property, plant and equipment, net by geography:
|  | December 31,
(in millions) |  | 2024 |  | 2023
U.S. |  | $ | 4,787 |  |  | 4,691 |
International(1) |  | 627 |  |  | 626 |
Total |  | $ | 5,414 |  |  | $ | 5,317 |
_______________________________ (1) All individual international locations accounted for less than 10% of the total balances.

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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 1 -SubTopic 10 -Topic 360 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482099/360-10-50-1 + Details
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