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FAIR VALUE MEASUREMENTS (Tables)
12 Months Ended
Dec. 31, 2024
Fair Value Disclosures [Abstract]  
Summary of Assets and Liabilities Measured at Fair Value
The following table summarizes the types of assets and liabilities measured at fair value on a recurring basis by level within the fair value hierarchy:
 December 31, 2024December 31, 2023
(in millions)Level 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets:        
Available-for-sale debt securities(1):
U.S. treasury securities$— $— $— $— $426 $— $— $426 
U.S. government agencies securities— — — — — 127 — 127 
Non-U.S. government securities— — — — — 10 — 10 
Certificates of deposit— — — — — 45 — 45 
Corporate debt securities— — — — — 1,451 — 1,451 
Residential mortgage and asset-backed securities— — — — — 367 — 367 
Equity securities:
Money market funds8,502 — — 8,502 4,465 — — 4,465 
Publicly traded equity securities(2)
1,561 — — 1,561 1,458 — — 1,458 
Deferred compensation plan343 — — 343 284 — — 284 
Foreign currency derivative contracts— 128 — 128 — — 
Total$10,405 $128 $— $10,533 $6,633 $2,007 $— $8,639 
Liabilities:
Contingent consideration liability$— $— $206 $206 $— $— $228 $228 
Deferred compensation plan343 — — 343 283 — — 283 
Foreign currency derivative contracts— — — 59 — 59 
Total$343 $$206 $552 $283 $59 $228 $570 
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(1)    During the three months ended March 31, 2024, we sold all of our available-for-sale debt securities and used the proceeds to partially fund our acquisition of CymaBay Therapeutics, Inc. (“CymaBay”) discussed in Note 6. Acquisitions.
(2)    Publicly traded equity securities include our investment in Arcellx, Inc. (“Arcellx”) of $515 million as of December 31, 2024, which is subject to contractual sale restrictions until June 2025. See Note 7. Collaborations and Other Arrangements for additional information.
Summary of Change in Fair Value of Contingent Consideration
The following table summarizes the change in fair value of our contingent consideration liability:
Year Ended December 31,
(in millions)20242023
Beginning balance$228 $275 
Changes in valuation assumptions(1)
(7)(60)
Effect of foreign exchange remeasurement(2)
(14)12 
Ending balance(3)
$206 $228 
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(1)    Included in Research and development expenses on our Consolidated Statements of Operations. The change in 2023 primarily related to changes in assumptions around probability and timing of regulatory approval.
(2)    Included in Other (income) expense, net on our Consolidated Statements of Operations.
(3)    Included in Other long-term obligations on our Consolidated Balance Sheets.
Summary of Estimated Fair Value and Carrying Value of Unsecured Notes and Liability of Future Royalty
The following table summarizes the total estimated fair value and carrying value of our senior unsecured notes, determined using Level 2 inputs based on their quoted market values:
December 31,
(in millions)20242023
Fair value$23,335 $22,567 
Carrying value$25,562 $23,834