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REVENUES - Summary of Disaggregation of Revenues (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Disaggregation of Revenue [Line Items]        
Total revenues $ 7,803 $ 7,082 $ 14,763 $ 13,749
U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 5,603 5,051 10,529 9,719
Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 1,324 1,189 2,469 2,273
Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 876 842 1,765 1,757
Total product sales        
Disaggregation of Revenue [Line Items]        
Total revenues 7,627 7,054 14,574 13,668
Total product sales | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 5,601 5,038 10,527 9,669
Total product sales | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 1,155 1,178 2,292 2,251
Total product sales | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 872 838 1,755 1,747
Total HIV        
Disaggregation of Revenue [Line Items]        
Total revenues 5,693 5,088 10,723 9,675
Total HIV | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 4,659 4,096 8,663 7,760
Total HIV | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 640 624 1,248 1,177
Total HIV | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 393 368 812 738
Biktarvy        
Disaggregation of Revenue [Line Items]        
Total revenues 3,772 3,530 7,133 6,679
Biktarvy | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 2,981 2,799 5,553 5,272
Biktarvy | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 468 429 905 804
Biktarvy | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 323 302 675 603
Descovy        
Disaggregation of Revenue [Line Items]        
Total revenues 967 653 1,774 1,239
Descovy | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 921 601 1,682 1,139
Descovy | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 23 24 46 45
Descovy | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 23 28 46 55
Genvoya        
Disaggregation of Revenue [Line Items]        
Total revenues 289 377 553 741
Genvoya | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 236 322 451 627
Genvoya | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 37 40 70 79
Genvoya | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 16 16 32 35
Odefsey        
Disaggregation of Revenue [Line Items]        
Total revenues 239 298 461 579
Odefsey | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 171 221 324 436
Odefsey | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 58 66 117 123
Odefsey | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 10 11 19 20
Symtuza - Revenue share        
Disaggregation of Revenue [Line Items]        
Total revenues 138 124 275 238
Symtuza - Revenue share | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 105 88 211 170
Symtuza - Revenue share | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 30 33 59 62
Symtuza - Revenue share | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 3 3 5 6
Yeztugo        
Disaggregation of Revenue [Line Items]        
Total revenues 232 15 397 15
Yeztugo | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 223 15 382 15
Yeztugo | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 0 0 0 0
Yeztugo | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 9 0 16 0
Other HIV        
Disaggregation of Revenue [Line Items]        
Total revenues 56 92 129 183
Other HIV | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 23 50 59 101
Other HIV | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 24 33 51 63
Other HIV | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 10 9 19 19
Total Liver Disease        
Disaggregation of Revenue [Line Items]        
Total revenues 877 795 1,644 1,553
Total Liver Disease | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 433 413 795 748
Total Liver Disease | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 193 170 363 338
Total Liver Disease | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 251 211 486 467
Livdelzi        
Disaggregation of Revenue [Line Items]        
Total revenues 167 78 300 118
Livdelzi | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 147 74 261 114
Livdelzi | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 20 4 39 4
Livdelzi | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 0 0 0 0
Sofosbuvir/Velpatasvir        
Disaggregation of Revenue [Line Items]        
Total revenues 303 342 586 687
Sofosbuvir/Velpatasvir | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 142 184 283 351
Sofosbuvir/Velpatasvir | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 81 81 141 161
Sofosbuvir/Velpatasvir | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 80 76 162 175
Vemlidy        
Disaggregation of Revenue [Line Items]        
Total revenues 289 252 526 504
Vemlidy | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 124 122 215 222
Vemlidy | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 13 13 27 24
Vemlidy | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 152 117 284 257
Other Liver Disease        
Disaggregation of Revenue [Line Items]        
Total revenues 118 123 232 244
Other Liver Disease | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 20 33 35 61
Other Liver Disease | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 79 72 157 148
Other Liver Disease | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 19 19 40 35
Veklury        
Disaggregation of Revenue [Line Items]        
Total revenues 23 121 167 423
Veklury | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 14 51 126 250
Veklury | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 2 19 17 41
Veklury | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 7 50 25 132
Total Oncology        
Disaggregation of Revenue [Line Items]        
Total revenues 873 849 1,683 1,606
Total Oncology | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 468 427 871 808
Total Oncology | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 265 291 543 547
Total Oncology | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 140 131 269 252
Total Cell Therapy        
Disaggregation of Revenue [Line Items]        
Total revenues 417 485 824 949
Total Cell Therapy | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 161 203 311 403
Total Cell Therapy | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 173 196 356 376
Total Cell Therapy | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 83 86 157 171
Tecartus        
Disaggregation of Revenue [Line Items]        
Total revenues 70 92 146 171
Tecartus | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 29 41 59 82
Tecartus | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 34 41 71 72
Tecartus | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 8 9 16 17
Yescarta        
Disaggregation of Revenue [Line Items]        
Total revenues 346 393 679 779
Yescarta | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 132 162 252 321
Yescarta | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 139 154 285 304
Yescarta | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 75 77 142 154
Trodelvy        
Disaggregation of Revenue [Line Items]        
Total revenues 457 364 859 657
Trodelvy | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 307 224 560 405
Trodelvy | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 92 96 187 171
Trodelvy | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 57 44 112 81
Total Other        
Disaggregation of Revenue [Line Items]        
Total revenues 161 202 357 410
Total Other | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 26 52 72 104
Total Other | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 55 73 122 149
Total Other | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 80 77 163 158
AmBisome        
Disaggregation of Revenue [Line Items]        
Total revenues 110 129 248 268
AmBisome | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 4 7 11 13
AmBisome | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 47 65 106 132
AmBisome | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 59 56 131 123
Other        
Disaggregation of Revenue [Line Items]        
Total revenues 51 73 109 143
Other | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 22 44 61 91
Other | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 8 8 16 16
Other | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues 21 21 32 35
Royalty, contract and other revenues        
Disaggregation of Revenue [Line Items]        
Total revenues 176 27 189 81
Royalty, contract and other revenues | U.S.        
Disaggregation of Revenue [Line Items]        
Total revenues 2 13 2 49
Royalty, contract and other revenues | Europe        
Disaggregation of Revenue [Line Items]        
Total revenues 169 10 177 21
Royalty, contract and other revenues | Rest of World        
Disaggregation of Revenue [Line Items]        
Total revenues $ 4 $ 4 $ 10 $ 10