<SEC-DOCUMENT>0001225208-13-006460.txt : 20130304
<SEC-HEADER>0001225208-13-006460.hdr.sgml : 20130304
<ACCEPTANCE-DATETIME>20130304190209
ACCESSION NUMBER:		0001225208-13-006460
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20130228
FILED AS OF DATE:		20130304
DATE AS OF CHANGE:		20130304

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Germano Geno J
		CENTRAL INDEX KEY:			0001424383

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-03619
		FILM NUMBER:		13663284

	MAIL ADDRESS:	
		STREET 1:		5 GIRALDA FARMS
		CITY:			MADISON
		STATE:			NJ
		ZIP:			07940

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PFIZER INC
		CENTRAL INDEX KEY:			0000078003
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				135315170
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		235 E 42ND ST
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2125732323

	MAIL ADDRESS:	
		STREET 1:		235 E 42ND ST
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PFIZER CHARLES & CO INC
		DATE OF NAME CHANGE:	19710908
</SEC-HEADER>
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    <periodOfReport>2013-02-28</periodOfReport>

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        <issuerCik>0000078003</issuerCik>
        <issuerName>PFIZER INC</issuerName>
        <issuerTradingSymbol>PFE</issuerTradingSymbol>
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            <rptOwnerName>Germano Geno J</rptOwnerName>
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            <rptOwnerStreet1>PFIZER INC.-CORP. SECRETARY</rptOwnerStreet1>
            <rptOwnerStreet2>235 EAST 42ND ST.</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10017</rptOwnerZipCode>
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            <isOfficer>1</isOfficer>
            <officerTitle>Business Unit President</officerTitle>
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                    <value>By children</value>
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                <natureOfOwnership>
                    <value>By Rule 16b-3 Plan</value>
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            </ownershipNature>
        </nonDerivativeHolding>
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    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Phantom Stock Units SSP</value>
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                <transactionPricePerShare>
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                <footnoteId id="F6"/>
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            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                <underlyingSecurityShares>
                    <value>12.0000</value>
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                <sharesOwnedFollowingTransaction>
                    <value>5317.0000</value>
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                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
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        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Appreciation Rights</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>27.3700</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2013-02-28</value>
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                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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                <transactionShares>
                    <value>165198.0000</value>
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                <transactionPricePerShare>
                    <value>0.0000</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2018-02-28</value>
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            </exerciseDate>
            <expirationDate>
                <value>2018-02-28</value>
                <footnoteId id="F7"/>
            </expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                    <value>165198.0000</value>
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                    <value>165198.0000</value>
                </sharesOwnedFollowingTransaction>
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                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
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        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Appreciation Rights</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>27.3700</value>
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                <value>2013-02-28</value>
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                    <value>137112.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.0000</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2020-02-28</value>
                <footnoteId id="F8"/>
            </exerciseDate>
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                <value>2020-02-28</value>
                <footnoteId id="F8"/>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                    <value>137112.0000</value>
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    <footnotes>
        <footnote id="F1">The reported transaction constitutes the earn-out of Performance Share Awards (including dividend equivalents thereon).</footnote>
        <footnote id="F2">The reported transaction constitutes the grant of restricted stock units, which are subject to certain vesting requirements.</footnote>
        <footnote id="F3">The reported transaction constitutes the withholding of shares to satisfy tax obligations upon the earn-out of Performance Share Awards (including dividend equivalents thereon).</footnote>
        <footnote id="F4">I hereby disclaim beneficial ownership of all shares held by members of my family.</footnote>
        <footnote id="F5">Each unit represents one phantom share of common stock.</footnote>
        <footnote id="F6">These units, which were acquired pursuant to the Pfizer Inc. Nonfunded Deferred Compensation and Supplemental Savings Plan, are settled in cash following the reporting person's separation from service and may be transferred by the reporting person into an alternative investment account at any time.</footnote>
        <footnote id="F7">The stock appreciation rights, which are subject to certain vesting requirements, will be settled in shares of Pfizer common stock on the fifth anniversary of the date of grant.</footnote>
        <footnote id="F8">The stock appreciation rights, which are subject to certain vesting requirements, will be settled in shares of Pfizer common stock on the seventh anniversary of the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Lawrence A. Fox, by power of atty., for Geno J. Germano</signatureName>
        <signatureDate>2013-03-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
