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Acquisition, Divestitures, Licensing Arrangements, Collaborative Arrangements and Privately Held Investment - Licensing Arrangement (Details) - Licensing Arrangement [Member] - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Sep. 30, 2018 | Sep. 30, 2018 | Apr. 01, 2018 | Sep. 30, 2018 | Dec. 31, 2016
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Proceeds from licensing arrangement |  |  |  | $ 40 |
Shire [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Proceeds from licensing arrangement |  | $ 35 | $ 75 | $ 110 |
Maximum amount of possible development and sales-based milestone payments and potential future royalty payments |  |  |  |  | $ 460
BionTech [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Maximum amount of possible development and sales-based milestone payments and potential future royalty payments | $ 325 |  |  |  |
Other (Income)/Deductions, Net [Member] | Shire [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Proceeds from licensing arrangement |  |  | $ 75 |  | $ 90
Research and Development Expense [Member] | BionTech [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Upfront payment for licensing arrangement | $ 50 |  |  |  |
Long-term Investments [Member] | BionTech [Member] |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Shares purchased (in shares) |  | 169,670 |  |  |
Value of shares purchased |  | $ 50 |  |  |

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- Definition Licensing Arrangement, Milestone, Maximum, Value + References No definition available. + Details
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