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Acquisitions, Divestitures, Assets and Liabilities Held for Sale, Licensing Arrangements, Research and Development and Collaborative Arrangements, Equity-Method Investments and Privately Held Investment - Licensing Arrangements (Details) - Licensing Agreements [Member] - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Sep. 30, 2018 | Sep. 30, 2018 | Apr. 01, 2018 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Proceeds from licensing arrangement |  |  |  |  | $ 101 | $ 33
Shire [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Proceeds from licensing arrangement |  | $ 35 | $ 75 | $ 110 |  |
Licensing arrangement, maximum potential milestones |  |  |  |  |  | 460
Shire [Member] | Other Nonoperating Income (Expense) [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Proceeds from licensing arrangement |  |  | $ 75 |  |  | $ 90
BionTech [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Licensing arrangement, maximum potential milestones | $ 325 |  |  |  |  |
BionTech [Member] | Research and Development Expense [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Payment for licensing arrangement | $ 50 |  |  |  |  |
Long-term Investments [Member] | BionTech [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Number of shares purchased |  | 169,670 |  |  |  |
Value of shares purchased |  | $ 50 |  |  |  |

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- Definition Licensing Arrangement, Milestone, Maximum, Value + References No definition available. + Details
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- Definition Licensing Arrangement, Number Of Shares Purchased + References No definition available. + Details
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- Definition Licensing Arrangement, Value Of Shares Purchased + References No definition available. + Details
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- Definition Proceeds From Licensing Arrangement + References No definition available. + Details
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- Details
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- Details
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- Details
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