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Acquisitions, Divestitures, Assets and Liabilities Held for Sale, Licensing Arrangements, Research and Development and Collaborative Arrangements, Equity-Method Investments and Privately Held Investment - Privately Held Investment (Details) - AM Pharma BV [Member] - USD ($) $ in Millions | 1 Months Ended |
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Apr. 30, 2015 | Dec. 31, 2017
Schedule of Equity Method Investments [Line Items] |  |
Impairment of investment |  | $ 43.0
Long-term Investments [Member] |  |
Schedule of Equity Method Investments [Line Items] |  |
Cost method investment, upfront and milestone payments | $ 87.5 |

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