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Acquisitions, Divestitures, Assets and Liabilities Held for Sale, Licensing Arrangements, Research and Development and Collaborative Arrangements, Equity-Method Investments and Privately Held Investment - Bamboo Therapeutics, Inc. (Details) - USD ($) $ in Millions |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Aug. 01, 2016 | Oct. 02, 2016 | Apr. 03, 2016 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |
Cash payments for acquisition, net of cash acquired | [1] |  |  |  | $ 0 |  | $ 1,000 |  | $ 18,368
Goodwill |  |  |  |  | $ 53,411 | [2] | $ 55,952 | [2] | $ 54,449
Bamboo Therapeutics [Member] |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |
Total consideration transferred |  | $ 150 |  |  |  |  |  |  |
Potential milestone payments |  | 495 |  |  |  |  |  |  |
Consideration transferred, including equity interest held prior to business combination |  | 343 |  |  |  |  |  |  |
Payments to acquire businesses, cash portion |  | 130 |  | $ 43 |  |  |  |  |
Cash payments for acquisition, net of cash acquired |  | 101 |  |  |  |  |  |  |
Assumed contingent consideration |  | 167 |  |  |  |  |  |  |
Fair value of previously held equity interest in acquiree |  | 45 |  |  |  |  |  |  |
Goodwill |  | 142 |  |  |  |  |  |  |
Net deferred tax liabilities |  | 94 |  |  |  |  |  |  |
Bamboo Therapeutics [Member] | Other Nonoperating Income (Expense) [Member] |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |
Gain recognized |  |  | $ 2 |  |  |  |  |  |
In Process Research and Development [Member] | Bamboo Therapeutics [Member] |  |  |  |  |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |
Intangible assets |  | $ 330 |  |  |  |  |  |  |
[1] | Amounts may not add due to rounding.
[2] | Amounts may not add due to rounding.

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