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Basis of Presentation and Significant Accounting Policies - Summary of Change in Accounting Principle (Details) - USD ($)
$ / shares in Units, $ in Millions
 3 Months Ended
Apr. 04, 2021
Mar. 29, 2020
Dec. 31, 2020
Condensed Consolidated Statements of Income:      
Other (income)/deductions––net $ (1,004) $ 190  
Income from continuing operations before provision for taxes on income 5,683 2,842  
Provision for taxes on income 805 359  
Income from discontinued operations––net of tax 9 881  
Net income before allocation to noncontrolling interests 4,886 3,364  
Net income attributable to Pfizer Inc. common shareholders $ 4,877 $ 3,355  
Earnings per common share––basic:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.87 $ 0.45  
Income from discontinued operations––net of tax (in dollars per share) 0 0.16  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) 0.87 0.60  
Earnings per common share––diluted:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) 0.86 0.44  
Income from discontinued operations––net of tax (in dollars per share) 0 0.16  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.86 $ 0.60  
Condensed Consolidated Statements of Comprehensive Income:      
Foreign currency translation adjustments, net $ 465 $ (1,256)  
Benefit plans: actuarial gains/(losses), net 0 0  
Reclassification adjustments related to amortization 0 0  
Reclassification adjustments related to settlements, net 0 0  
Other 0 0  
Tax provision/(benefit) on other comprehensive income/(loss) 84 (380)  
Condensed Consolidated Statements of Cash Flows:      
Deferred taxes from continuing operations 199 82  
Benefit plan contributions in excess of expense/income (373) (276)  
Condensed Consolidated Balance Sheets:      
Noncurrent deferred tax assets and other noncurrent tax assets 2,537   $ 2,383
Other noncurrent assets 4,744   4,569
Pension benefit obligations 4,526   4,766
Retained earnings 95,158   90,392
Accumulated other comprehensive loss (4,664)   (5,310)
Previous Accounting Principle [Member]      
Condensed Consolidated Statements of Income:      
Other (income)/deductions––net (857) 216  
Income from continuing operations before provision for taxes on income 5,536 2,817  
Provision for taxes on income 773 355  
Income from discontinued operations––net of tax 9 948  
Net income before allocation to noncontrolling interests 4,772 3,410  
Net income attributable to Pfizer Inc. common shareholders $ 4,763 $ 3,401  
Earnings per common share––basic:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.85 $ 0.44  
Income from discontinued operations––net of tax (in dollars per share) 0 0.17  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) 0.85 0.61  
Earnings per common share––diluted:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) 0.84 0.44  
Income from discontinued operations––net of tax (in dollars per share) 0 0.17  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.84 $ 0.61  
Condensed Consolidated Statements of Comprehensive Income:      
Foreign currency translation adjustments, net $ 546 $ (1,272)  
Benefit plans: actuarial gains/(losses), net 47 (166)  
Reclassification adjustments related to amortization 75 66  
Reclassification adjustments related to settlements, net 19 53  
Other (81) 16  
Tax provision/(benefit) on other comprehensive income/(loss) 72 (377)  
Condensed Consolidated Statements of Cash Flows:      
Deferred taxes from continuing operations 167 77  
Benefit plan contributions in excess of expense/income (226) (250)  
Condensed Consolidated Balance Sheets:      
Noncurrent deferred tax assets and other noncurrent tax assets 2,569   2,383
Other noncurrent assets 4,738   4,569
Pension benefit obligations 4,527   4,766
Retained earnings 95,044   96,770
Accumulated other comprehensive loss (4,523)   (11,688)
Impact of Change [Member]      
Condensed Consolidated Statements of Income:      
Other (income)/deductions––net (146) (25)  
Income from continuing operations before provision for taxes on income 146 25  
Provision for taxes on income 32 4  
Income from discontinued operations––net of tax 0 (68)  
Net income before allocation to noncontrolling interests 114 (47)  
Net income attributable to Pfizer Inc. common shareholders $ 114 $ (47)  
Earnings per common share––basic:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.02 $ 0  
Income from discontinued operations––net of tax (in dollars per share) 0 (0.01)  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) 0.02 (0.01)  
Earnings per common share––diluted:      
Income from continuing operations attributable to Pfizer Inc. common shareholders (in dollars per share) 0.02 0  
Income from discontinued operations––net of tax (in dollars per share) 0 (0.01)  
Net income attributable to Pfizer Inc. common shareholders (in dollars per share) $ 0.02 $ (0.01)  
Condensed Consolidated Statements of Comprehensive Income:      
Foreign currency translation adjustments, net $ (81) $ 16  
Benefit plans: actuarial gains/(losses), net (47) 166  
Reclassification adjustments related to amortization (75) (66)  
Reclassification adjustments related to settlements, net (19) (53)  
Other 81 (16)  
Tax provision/(benefit) on other comprehensive income/(loss) 12 (3)  
Condensed Consolidated Statements of Cash Flows:      
Deferred taxes from continuing operations 32 4  
Benefit plan contributions in excess of expense/income (146) $ (25)  
Condensed Consolidated Balance Sheets:      
Noncurrent deferred tax assets and other noncurrent tax assets (32)   0
Other noncurrent assets 6   0
Pension benefit obligations 0   0
Retained earnings 114   (6,378)
Accumulated other comprehensive loss $ (141)   $ 6,378