<SEC-DOCUMENT>0001225208-21-011946.txt : 20210902
<SEC-HEADER>0001225208-21-011946.hdr.sgml : 20210902
<ACCEPTANCE-DATETIME>20210902160801
ACCESSION NUMBER:		0001225208-21-011946
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20210830
FILED AS OF DATE:		20210902
DATE AS OF CHANGE:		20210902

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MALIK AAMIR
		CENTRAL INDEX KEY:			0001881510

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-03619
		FILM NUMBER:		211233312

	MAIL ADDRESS:	
		STREET 1:		C/O PFIZER INC. CORPORATE SECRETARY
		STREET 2:		235 EAST 42ND STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PFIZER INC
		CENTRAL INDEX KEY:			0000078003
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				135315170
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		235 E 42ND ST
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2125732323

	MAIL ADDRESS:	
		STREET 1:		235 E 42ND ST
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PFIZER CHARLES & CO INC
		DATE OF NAME CHANGE:	19710908
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2021-08-30</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000078003</issuerCik>
        <issuerName>PFIZER INC</issuerName>
        <issuerTradingSymbol>PFE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001881510</rptOwnerCik>
            <rptOwnerName>MALIK AAMIR</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>PFIZER INC.-CORP. SECRETARY</rptOwnerStreet1>
            <rptOwnerStreet2>235 EAST 42ND ST.</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10017</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOfficer>1</isOfficer>
            <officerTitle>Executive Vice President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>374.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes></footnotes>

    <remarks>poaam21.htm</remarks>

    <ownerSignature>
        <signatureName>Susan E. Grant, by power of atty., for Aamir Malik</signatureName>
        <signatureDate>2021-09-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>poaam21.htm
<TEXT>
<html>
<head>
<title>Power of Attorney</title>

</head>

<body bgcolor="#FFFFFF" text="#000000">

<p align="center"><u><strong>POWER OF ATTORNEY</strong></u><br>
</p>
<p>The  undersigned hereby constitutes and appoints each of Tara J. Gabbai, Susan E. Grant, Lori P. Hernando, Margaret M. Madden, Madelyn D. Purcell and Shehzad Siddiqui as  the undersigned&rsquo;s true and lawful attorney-in-fact and agent, and grants each  of them full power to act on behalf of the undersigned and in the undersigned&rsquo;s  name, place and stead, in any and all capacities, for the purpose of completing  and signing, on behalf of the undersigned, </p>
<ul type="disc">
  <li>any       Form 3, Form 4 or Form 5 required or permitted to be filed by the       undersigned pursuant to Section 16 of the Securities Exchange Act of 1934,       as amended (the &ldquo;Exchange Act&rdquo;), </li>
  <li>any       Form 144 required to be filed by the undersigned under the Securities Act       of 1933, as amended (the &ldquo;Securities Act&rdquo;), and Rule 144 promulgated       thereunder, and </li>
  <li>any and       all other documents, including, without limitation, Form ID, necessary or desirable to facilitate the filing by the       undersigned of Form 144 and forms under Section 16 of the Exchange Act, &nbsp;<br>
  </li>
</ul>
<p>with regard to the  undersigned's ownership of or transactions in securities of Pfizer Inc.,  including, without limitation, the power to complete and sign any and all  amendments to such forms and documents, if any, and to file such forms and  documents and amendments thereto with the Securities and Exchange Commission,  and to do and perform each and every act and thing requisite or necessary to be  done in connection with such forms and documents and amendments thereto, as  fully and to all intents and purposes as the undersigned might or could do in person.&nbsp; </p>
<p>The authority  of Tara J. Gabbai, Susan E. Grant, Lori P. Hernando, Margaret M. Madden, Madelyn D. Purcell and Shehzad Siddiqui under this Power of Attorney shall continue  until the undersigned is no longer required to file Form 3, Form 4, Form 5 or  Form 144 with regard to the undersigned's ownership of or transactions in  securities of Pfizer Inc., unless earlier revoked in writing.&nbsp; The undersigned acknowledges that  Tara J. Gabbai, Susan E. Grant, Lori P. Hernando, Margaret M. Madden, Madelyn D. Purcell and Shehzad Siddiqui are not assuming any of the undersigned's responsibilities to comply  with Rule 144 under the Securities Act or Section 16 of the Exchange Act.</p>
<p>&nbsp;</p>
<p>Signature:&nbsp;<u> /s/Aamir Malik<br>
  </u>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Aamir Malik</p>
<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>
<p>Date: August 30, 2021</p>
</body>
</html>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
