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Acquisition, Discontinued Operations, Equity-Method Investment and Collaborative Arrangement - Collaborative Arrangements (Detail) - USD ($) $ / shares in Units, $ in Millions |  | 1 Months Ended
--- | --- | ---
Jan. 04, 2022 | Oct. 31, 2022
Biohaven [Member] | Subsequent Event [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Business acquisition, per share in cash (in dollars per share) |  | $ 148.50
Payments for acquisition, cash portion |  | $ 11,500
Collaborative Arrangement [Member] | Biohaven [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Payment to collaborators | $ 500 |
Upfront payment to collaborators | 150 |
Committed investment from collaborator | 350 |
Collaborative Arrangement [Member] | Biohaven [Member] | Acquired In-Process Research and Development Expense [Member] |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |
Upfront payment and premium paid in equity investment | $ 263 |

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