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Restructuring Charges and Other Costs Associated with Acquisitions and Cost-Reduction/Productivity Initiatives (Tables)

9 Months Ended

Sep. 28, 2025

Restructuring and Related Activities [Abstract]

Schedule of Acquisitions and Cost-Reduction/Productivity Initiatives

The following summarizes costs and credits for acquisitions and cost-reduction/productivity initiatives:
						Three Months Ended												Nine Months Ended
(MILLIONS)						September 28, 2025						September 29, 2024						September 28, 2025						September 29, 2024
Restructuring charges/(credits):
Employee terminations						$	124					$	25					$	360					$	1,009
Asset impairments						111						111						328						177
Exit costs						2						82						96						145
Restructuring charges/(credits)(a)						237						217						784						1,331
Transaction costs(b)						—						—						—						5
Integration costs and other(c)						49						96						162						333
Restructuring charges and certain acquisition-related costs						286						313						945						1,669
Net periodic benefit costs/(credits) recorded in Other (income)/deductions––net						(6)						2						(74)						7
Inventory write-offs––recorded in Cost of sales						33						—						33						—
Additional depreciation––asset restructuring recorded in our condensed consolidated statements of operations as follows(d):
Cost of sales						3						6						10						11
Selling, informational and administrative expenses						—						2						—						5
Research and development expenses						1						—						1						—
Total additional depreciation––asset restructuring						4						8						11						16
Implementation costs recorded in our condensed consolidated statements of operations as follows(e):
Cost of sales						26						30						72						95
Selling, informational and administrative expenses						26						13						46						77
Research and development expenses						53						33						116						66
Total implementation costs						105						75						234						238
Total costs associated with acquisitions and cost-reduction/productivity initiatives						$	423					$	398					$	1,150					$	1,930

(a)Primarily represents cost-reduction initiatives. Amounts associated with our Biopharma segment: (i) charges of $240 million for the three months ended September 28, 2025 (including charges of $117 million for our Manufacturing Optimization Program and charges of $107 million for our Realigning our Cost Base Program), (ii) charges of $451 million for the nine months ended September 28, 2025 (including charges of $669 million for our Realigning our Cost Base Program and credits of $295 million for our Manufacturing Optimization Program), (iii) charges of $141 million for the three months ended September 29, 2024 (primarily including charges for our Realigning our Cost Base Program) and (iv) charges of $1.2 billion for the nine months ended September 29, 2024 (including charges of $1.3 billion for our Manufacturing Optimization Program and credits of $69 million for our Realigning our Cost

Base Program). For the nine months ended September 28, 2025 and September 29, 2024, Employee terminations include revisions of estimates of previously recorded accruals for severance benefits, driven in large part by higher-than-expected voluntary attrition.

(b)Represents external costs for banking, legal, accounting and other similar services.

(c)Represents external, incremental costs directly related to integrating acquired businesses, such as expenditures for consulting and the integration of systems and processes, and certain other qualifying costs.

(d)Represents the impact of changes in the estimated useful lives of assets involved in restructuring actions.

(e)Represents incremental costs directly related to implementing our non-acquisition-related cost-reduction/productivity initiatives.

Schedule of Components and Changes in Restructuring Accruals

The following summarizes the components and changes in restructuring accruals:
(MILLIONS)						Employee Termination Costs						Asset Impairment Charges						Exit Costs						Accrual
Balance, December 31, 2024(a)						$	2,046					$	—					$	74					$	2,120
Provision						360						328						96						784
Utilization and other(b)						(724)						(328)						(15)						(1,067)
Balance, September 28, 2025(c)						$	1,682					$	—					$	155					$	1,836

(a)Included in Other current liabilities ($1.7 billion) and Other noncurrent liabilities ($437 million).

(b)Other activity includes adjustments for foreign currency translation that are not material to our condensed consolidated financial statements.

(c)Included in Other current liabilities ($1.3 billion) and Other noncurrent liabilities ($532 million).

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Tabular disclosure of costs incurred for restructuring including, but not limited to, exit and disposal activities, remediation, implementation, integration, asset impairment, and charges against earnings from the write-down of assets.

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Tabular disclosure of an entity's restructuring reserve that occurred during the period associated with the exit from or disposal of business activities or restructurings for each major type of cost. This element may also include a description of any reversal and other adjustment made during the period to the amount of an accrued liability for restructuring activities. This element may be used to encapsulate the roll forward presentations of an entity's restructuring reserve by type of cost and in total, and explanation of changes that occurred in the period.

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