EX-21 5 mdt-202510kxex21.htm EX-21
Exhibit 21

Medtronic plc and Subsidiaries |  |  |  |
At April 25, 2025 |  |  |  |

Company | Jurisdiction of Formation
2074417 Alberta ULC | Canada
A&E Products de Honduras S.A. | Honduras
A&E Products do Brasil Ltda. | Brazil
A&E Products Group, Inc. | Delaware
Advanced Medical Technologies GmbH | Germany
Affera, Inc. | Delaware
AI Biomed Corp | California
Aircraft Medical Ltd. | United Kingdom
Airox | France
Arterial Vascular Engineering Canada, Company | Canada
Arterial Vascular Engineering UK Limited | United Kingdom
Auto Suture do Brasil Ltda. | Brazil
Avenu Medical, Inc. | Delaware
Batts LLC | Delaware
Batts, Inc. | Delaware
Between Investeringsgroep B.V. | Netherlands
Biostar Biomedikal Mühendislik Anonim Sirketi | Turkey
Bo Yao (Shanghai) Medical Device Co. Ltd. | China
CardioInsight Technologies Inc. | Delaware
Carlisle Philippines, Inc. | Philippines
Carmel Biosensors Ltd. | Israel
CCI Istanbul Teknolojik Hizmetler Limited Sirketi | Turkey
Changzhou Chuangzhihui Incubator Management Co., Ltd. | China
Changzhou Kangdi Medical Stapler Co., Ltd. | China
Changzhou Kanghui Medical Innovation Co., Ltd. | China
CircuLite, Inc. | Delaware
Comercial Medtronic Chile Limitada | Chile
Companion Medical, Inc. | Delaware
Covidien (China) Medical Devices Technology Co., Ltd. | China
Covidien (Shanghai) Management Consulting Co., Ltd. | China
Covidien Adhesives Italia Srl | Italy
Covidien AG | Switzerland
Covidien Argentina S.A. | Argentina
Covidien Canada Holdings LLC | Delaware
Covidien Caribbean, Inc. | Delaware
Covidien Delaware VI Corp. | Delaware
Covidien Eurasia LLC | Russia
Covidien France Holdings, Inc. | Connecticut
Covidien Group Holdings Limited | Bermuda

Covidien Group S.à.r.l. | Luxembourg
Covidien Healthcare International Trading (Shanghai) Co., Ltd. | China
Covidien Holding Inc. | Delaware
Covidien Holdings International Corporation | Delaware
Covidien Holdings S.à.r.l. | Luxembourg
Covidien International (US) Holdings A, LLC | Delaware
Covidien International Finance S.A. | Luxembourg
Covidien International S.à.r.l. | Luxembourg
Covidien Ireland Limited | Ireland
Covidien Israel Holdings Ltd | Israel
Covidien Israel Investments Ltd | Israel
Covidien Israel Surgical Research Ltd | Israel
Covidien Japan, Inc. | Japan
Covidien llc | Delaware
Covidien LP | Delaware
Covidien Manufacturing Grenoble | France
Covidien Medical Products (Shanghai) Manufacturing L.L.C. | China
Covidien Peru S.A. | Peru
Covidien Philippines, Inc. | Philippines
Covidien Private Limited | Singapore
Covidien Pty Limited | Australia
Covidien Sales LLC | Delaware
Covidien Swiss Holding GmbH | Switzerland
Covidien UK Holding Ltd | United Kingdom
Covidien Limited | Ireland
Covidien Uruguay S.A. | Uruguay
Covidien US Holdings, Inc. | Delaware
Covidien Ventures Ltd. | Bermuda
Davis & Geck Caribe Limited | Cayman Islands
Diabeter Nederland B.V. | Netherlands
Digital Surgery Limited | United Kingdom
Epix Therapeutics, Inc. | Delaware
Ev3, Inc. | Delaware
First Lafayette Holdings LLC | Delaware
Floreane Medical Implants | France
Fortimedix Assets II B.V. | Netherlands
Fortimedix Innovation B.V. | Netherlands
Fortimedix Surgical B.V. | Netherlands
Fortimedix USA, Inc. | California
GC Holdings, Inc. | Delaware
Georgia Packaging, LLC | Delaware
Given Imaging, Inc. | Delaware
Given Imaging B.V. | Netherlands
Given Imaging Ltd. | Israel
Given Imaging Vietnam Co., Ltd. | Vietnam
Graphic Controls (Barbados), Ltd. | Barbados

HBX, Inc. | Kentucky
HeartWare, Inc. | Delaware
HeartWare International LLC | Delaware
IHS Health Services Egypt LLC | Egypt
IHS Health Services Lebanon Sarl | Lebanon
IHS Health Services Pakistan (Private) Limited | Pakistan
IHS Saglik Hizmetleri Ltd STI | Turkey
India Medtronic Private Limited | India
Integrated Health Solutions Chile S.A. | Chile
Integrated Health Solutions International Sàrl | Switzerland
Intersect ENT, Inc. | Delaware
Invatec S.p.A. | Italy
Invatec Technology Center GmbH | Switzerland
Kangaroo US HoldCo, Inc. | Delaware
Kendall de Mexico, S.A. de C.V. | Mexico
Kendall de Venezuela, C.A. | Venezuela
Kendall S.A. | Panama
KLHC, Inc. | Delaware
Klue, Inc. | Delaware
Kyphon South Africa (Proprietary) Ltd. | South Africa
Life Design Systems, Inc. | Wisconsin
M-Smart Medical Technology (Shanghai) Co. Ltd. | China
Makani II Unlimited Company | Ireland
Mallinckrodt DAR Srl | Italy
Mallinckrodt Holdings, LLC | Delaware
Mallinckrodt Holdings B.V. | Netherlands
Mallinckrodt Medical Unlimited Company | Ireland
Mallinckrodt US LLC | Delaware
Marblehead Medical LLC | Minnesota
Mazor Robotics Ltd. | Israel
MDT Sub Holdings, Inc. | Delaware
MDT Turkey Finansal Danışmanlık Limited Şirketi | Turkey
Medical Education Y. K. | Japan
Medical Medtronic Nigeria Limited | Nigeria
Medicrea International | France
Medicrea USA, Corp | Delaware
Medina Medical, Inc. | Delaware
Medinse S. de R.L. de C.V. | Mexico
Medtronic – Sequoia (Cayman) Innovation Investment Management Partners, Ltd | Cayman Islands
Medtronic (Africa) (Proprietary) Limited | South Africa
Medtronic (Changzhou) Medical Devices Technology Co., Ltd. | China
Medtronic (Chengdu) Management Consulting Co., Ltd. | China
Medtronic (Schweiz) A.G. (Medtronic (Suisse) S.A.) | Switzerland
Medtronic (Shanghai) Ltd. | China
Medtronic (Shanghai) Management Co. Ltd. | China
Medtronic (Taiwan) Ltd. | Taiwan

Medtronic (Thailand) Limited | Thailand
Medtronic Ablation Frontiers LLC | Delaware
Medtronic Adriatic d.o.o. | Croatia
Medtronic Advanced Energy LLC | Delaware
Medtronic Advanced Energy Luxembourg S.à.r.l. | Luxembourg
Medtronic AF Luxembourg S.à r.l. | Luxembourg
Medtronic AG | Switzerland
Medtronic Aktiebolag | Sweden
Medtronic Arabia Regional Headquarter | Saudi Arabia
Medtronic Ardian Luxembourg S.à.r.l. | Luxembourg
Medtronic ATS Medical, Inc. | Minnesota
Medtronic Australasia Pty Ltd | Australia
Medtronic B.V. | Netherlands
Medtronic Bakken Research Center B.V. | Netherlands
Medtronic Bangladesh Pvt. Ltd. | Bangladesh
Medtronic Belgium S.A./N.V. | Belgium
Medtronic BioPharma B.V. | Netherlands
Medtronic BioPharma Sàrl | Switzerland
Medtronic Bulgaria EOOD | Bulgaria
Medtronic Canada ULC | Canada
Medtronic Care Management Services, LLC | Minnesota
Medtronic Cash Pool LLC | Massachusetts
Medtronic Changzhou Medical Device Co., Ltd. | China
Medtronic China Kanghui Holdings | Cayman Islands
Medtronic China Venture Fund (Cayman), L.P. | Cayman Islands
Medtronic China, LLC. | Minnesota
Medtronic Colombia S.A. | Colombia
Medtronic Comercial Ltda. | Brazil
Medtronic Comercial Panamá, S.A. | Panama
Medtronic CoreValve LLC | Delaware
Medtronic Costa Rica. S.A. | Costa Rica
Medtronic CryoCath LP | Canada
Medtronic CV Luxembourg S.à.r.l. | Luxembourg
Medtronic Czechia s.r.o. | Czech Republic
Medtronic Danmark A/S | Denmark
Medtronic Diabetes (Chengdu) Co., Ltd. | China
Medtronic do Brasil Ltda. | Brazil
Medtronic Dominican Republic S.A.S. | Dominican Republic
Medtronic Dominicana (Manufactura), S.A. | Dominican Republic
Medtronic Egypt LLC | Egypt
Medtronic Empalme S. de R.L. de C.V. | Mexico
Medtronic Engineering and Innovation Center Private Limited | India
Medtronic Europe Limited | Malta
Medtronic Europe Sàrl | Switzerland
Medtronic Fabrication | France
Medtronic Finance Holdings ULC | Cayman Islands

Medtronic Finance Hungary Kft. | Hungary
Medtronic Finland Oy | Finland
Medtronic France | France
Medtronic GmbH | Germany
Medtronic Global Investments Unlimited Company | Ireland
Medtronic Global Holdings S.C.A. | Luxembourg
Medtronic GP S.à r.l. | Luxembourg
Medtronic Group Holding, Inc. | Minnesota
Medtronic Hellas Medical Device Commercial Single Member S.A. | Greece
Medtronic Holding, Inc. | Minnesota
Medtronic Holding B.V. | Netherlands
Medtronic Holding Hungary Kft. | Hungary
Medtronic Holding Switzerland G.m.b.H. | Switzerland
Medtronic Holdings France | France
Medtronic Holdings S.à.r.l. | Luxembourg
Medtronic Hong Kong Medical Limited | Hong Kong
Medtronic Hungaria Kereskedelmi Kft | Hungary
Medtronic Ibérica S.A. | Spain
Medtronic Innovation Center (Israel) Ltd | Israel
Medtronic Integrated Health Solutions LLC | Minnesota
Medtronic International, Ltd. | Delaware
Medtronic International Holding LLC | Minnesota
Medtronic International Technology, Inc. | Minnesota
Medtronic International Trading, Inc. | Minnesota
Medtronic International Trading Holding LLC | Delaware
Medtronic International Trading Pte. Ltd. | Singapore
Medtronic International Trading Sàrl | Switzerland
Medtronic Interventional Vascular, Inc. | Massachusetts
Medtronic Invatec LLC | Delaware
Medtronic IP Holding International Luxembourg S.à.r.l. | Luxembourg
Medtronic Ireland Limited | Ireland
Medtronic Ireland Manufacturing Unlimited Company | Ireland
Medtronic Italia S.p.A. | Italy
Medtronic Japan Co., Ltd. | Japan
Medtronic Jolife LLC | Delaware
Medtronic Kazakhstan Limited Liability Partnership | Kazakhstan
Medtronic KL Holdings LLC | Minnesota
Medtronic Korea Holdings Ltd. | South Korea
Medtronic Korea Ltd. | South Korea
Medtronic Labs PBC | Delaware
Medtronic Latin America, Inc. | Minnesota
Medtronic Limited | United Kingdom
Medtronic LLC | Russia
Medtronic Logistics LLC | Minnesota
Medtronic Luxembourg Global Holdings S.à r.l. | Luxembourg
Medtronic Malaysia Operations Sdn. Bhd | Malaysia

Medtronic Malaysia Sdn. Bhd. | Malaysia
Medtronic M E Trading LLC | United Arab Emirates
Medtronic Medical CR S de RL | Costa Rica
Medtronic Medikal Teknoloji Ticaret Limited Sirketi | Turkey
Medtronic Mediterranean Offshore SAL | Lebanon
Medtronic META FZ-LLC | United Arab Emirates
Medtronic Mexico S. de R.L. de C.V. | Mexico
Medtronic MiniMed, Inc. | Delaware
Medtronic MiniMed India Private Limited | India
Medtronic Monitoring, Inc. | Delaware
Medtronic Navigation, Inc. | Delaware
Medtronic Navigation Israel Ltd. | Israel
Medtronic New Zealand Limited | New Zealand
Medtronic Norge AS | Norway
Medtronic Oesterreich G.m.b.H. | Austria
Medtronic Pacific Trading, Inc. | Minnesota
Medtronic Pakistan (Private) Limited | Pakistan
Medtronic Philippines, Inc. | Philippines
Medtronic Poland Sp. Z o.o. | Poland
Medtronic Poland Finance Sp.z.o.o. | Poland
Medtronic Portugal, Lda | Portugal
Medtronic PS Medical, Inc. | California
Medtronic Puerto Rico Operations Co. | Cayman Islands
Medtronic RCS Holding GmbH | Switzerland
Medtronic Romania SRL | Romania
Medtronic S. de R.L. de C.V. | Mexico
Medtronic S.A.I.C. | Argentina
Medtronic Saudi Arabia Company | Saudi Arabia
Medtronic Servicios S. de R.L. de C.V. | Mexico
Medtronic Sequoia (Cayman) Innovation Investment Management Partners, Ltd. | Cayman Islands
Medtronic Shared Services Americas S.A.S. | Colombia
Medtronic Shared Services SRL | Costa Rica
Medtronic Singapore Operations Pte. Ltd. | Singapore
Medtronic Slovakia s.r.o. | Slovakia
Medtronic Sofamor Danek Co., Ltd. | Japan
Medtronic Sofamor Danek Deggendorf GmbH | Germany
Medtronic Sofamor Danek USA, Inc. | Tennessee
Medtronic Sofamor Danek, Inc. | Indiana
Medtronic Srbija d.o.o. Beograd-Novi Beograd | Serbia
Medtronic Sweden Finance AB | Sweden
Medtronic Trading Ltd. | Israel
Medtronic Trading NL BV | Netherlands
Medtronic Ukraine Limited Liability Company | Ukraine
Medtronic ULN, LLC | Delaware
Medtronic USA, Inc. | Minnesota
Medtronic Vascular Galway Unlimited Company | Ireland

Medtronic Vascular, Inc. | Delaware
Medtronic Ventor Technologies Ltd. | Israel
Medtronic Vietnam Company Limited | Vietnam
Medtronic VT, LLC | Delaware
Medtronic World Trade Corporation | Minnesota
Medtronic Xomed, Inc. | Delaware
Medtronic Xomed LLC | Delaware
Medtronic, Inc. | Minnesota
Medtronic, trgovina z medicinsko tehnologijo in opremo d.o.o. | Slovenia
Michigan Critical Care Consultants, Inc. | Michigan
Micro Therapeutics, Inc. | Maryland
MiniMed Australia | Australia
MiniMed Canada ULC | Canada
MiniMed Denmark ApS | Denmark
MiniMed Distribution Corp. | Delaware
MiniMed France S.A.S. | France
MiniMed Hellas Single Member LLC | Greece
MiniMed Holding B.V.- | Netherlands
MiniMed Holdings Switzerland Sàrl | Switzerland
MiniMed International Trading Sàrl | Switzerland
MiniMed Italy S.R.L. | Italy
MiniMed Netherlands B.V. | Netherlands
MiniMed Norway AS | Norway
MiniMed Philippines, Inc. | Philippines
MiniMed Portugal, Unipessoal Lda. | Portugal
MiniMed Pty Ltd | Australia
MiniMed Puerto Rico Operations Company | Cayman Islands
MiniMed Spain S.L. | Spain
MiniMed Te Austria GmbH | Austria
MiniMed Technologies Ireland Limited | Ireland
MiniMed (UK) Limited- | United Kingdom
MMed Sweden AB | Sweden
MMJ, S.A. de C.V. | Mexico
MSCH LLC | Delaware
N.G.C. Medical Srl | Italy
NayaMed International Sàrl | Switzerland
N.O.K. Nederlandse Obesitas Kliniek B.V. | Netherlands
Nederelandse Obesitas Kliniek Zuid B.V. | Netherlands
Nederlandse Obesitas Kliniek West B.V. | Netherlands
Nederlandse Obesitas kliniek Zeeland B.V. | Netherlands
Nellcor Puritan Bennett Ireland Holdings Unlimited Company | Ireland
Nellcor Puritan Bennett Ireland Unlimited Company | Ireland
Nellcor Puritan Bennett LLC | Delaware
Nellcor Puritan Bennett Mexico, S.A. de C.V. | Mexico
New Wave Surgical, LLC | Delaware
NPB Belgium B.V. | Belgium

NPB Finland Oy | Finland
NPB Germany GmbH | Germany
NPB Japan Co., Ltd. | Japan
Nutrino Health Ltd | Israel
Obesitas International B.V. | Netherlands
Obesitas Nederland B.V. | Netherlands
Old Colony State Insurance Company | Vermont
Oridion Capnography, Inc. | California
Oridion Medical 1987 Ltd. | Israel
Oridion Systems Ltd. | Israel
Osteotech, Inc. | Delaware
Plastics Holding Corporation | Nevada
Polyken Technologies Europe, Inc. | Delaware
Polysuture Industria e Comercio Ltda. | Brazil
PT. Covidien Indonesia | Indonesia
PT Medtronic Indonesia | Indonesia
PTB International LLC | Delaware
Raychem Tecnologias, S. de R.L. de C.V. | Mexico
Retail Group de Mexico S.A. de C.V. | Mexico
RF Surgical Systems LLC | Minnesota
Sanatis GmbH | Germany
Sapheon LLC | California
Shanghai MedTech Service Co., Ltd. | China
Shanghai Medtronic Zhikang Medical Devices Co., Ltd. | China
Shanghai Mei Jing Mwi Zhong Venture Capital Partnership (Limited Partnership) | China
Shanghai Mei Zhong Private Fund Management Co., Ltd. China | China
Shanghai MyanCor Medical Ltd | China
Sherwood Medical Company I | Delaware
Singapore MyanCor Medical Pte. Ltd. | Singapore
Societe De Fabrication de Material Orthopedique En Abrege Sofamor | France
Sofradim Production | France
SonarMed Inc. | Delaware
SpinalGraft Technologies, LLC | Tennessee
Superdimension, Inc. | Delaware
Suzhou Medtronic Venture Capital Partnership Enterprise (L.P.) | China
Suzhou Medtronic-Sequoia Innovation Investment Management Co., Ltd. | China
Titan Spine, Inc. | Delaware
Tissue Science Laboratories Limited | United Kingdom
Twelve, Inc. | Delaware
U.S.S.C. Puerto Rico, Inc. | Cayman Islands
U.S.S.C. Puerto Rico (NY), Inc. | New York
United States Surgical Corporation | Delaware
USSC FSC, Inc. | Barbados
USSC Medical GmbH | Germany
Valera Holdings S.à.r.l. | Luxembourg
Valleylab Holding Corporation | Delaware

Vascular Medcure, Inc. | Delaware
Visionsense Corp. | Delaware
Visionsense Ltd. | Israel
Vitatron Holding B.V. | Netherlands
VNUS Medical Technologies II, Inc. | Delaware
Warsaw Orthopedic Inc. | Indiana
WEM Equipamentos Electronicos Ltda. | Brazil
World Heart Corporation | Delaware
Zephyr Technology LLC | Delaware
Zorginitiatieven B.V. | Netherlands