    <SEC-DOCUMENT>0001308179-24-000454-index.html : 20240404
    <SEC-HEADER>0001308179-24-000454.hdr.sgml : 20240404
    <ACCEPTANCE-DATETIME>20240404160544
    ACCESSION NUMBER:		0001308179-24-000454
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20231231
    FILED AS OF DATE:		20240404
    DATE AS OF CHANGE:		20240404
    EFFECTIVENESS DATE:		20240404

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			VERTEX PHARMACEUTICALS INC / MA
    		CENTRAL INDEX KEY:			0000875320
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		IRS NUMBER:				043039129
    		STATE OF INCORPORATION:			MA
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	000-19319
    		FILM NUMBER:		24823169

    	BUSINESS ADDRESS:
    		STREET 1:		50 NORTHERN AVENUE
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02210
    		BUSINESS PHONE:		6173416393

    	MAIL ADDRESS:
    		STREET 1:		50 NORTHERN AVENUE
    		CITY:			BOSTON
    		STATE:			MA
    		ZIP:			02210
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>lvrtx2023_ars.pdf
    <DESCRIPTION>VERTEX PHARMACEUTICALS INC - ARS
    <TEXT>
    Document 1 - file: lvrtx2023_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>