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REVENUE - Disaggregation of Revenue by Product and Region (Details) - USD ($)
$ in Millions
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Revenue from External Customer [Line Items]    
Total Revenues $ 11,201 $ 11,865
Performance obligation satisfied in previous period 444 182
United States    
Revenue from External Customer [Line Items]    
Total Revenues 7,873 8,476
International    
Revenue from External Customer [Line Items]    
Total Revenues 3,110 3,190
Other    
Revenue from External Customer [Line Items]    
Total Revenues 218 199
Growth Portfolio    
Revenue from External Customer [Line Items]    
Total Revenues 5,563 4,792
Opdivo    
Revenue from External Customer [Line Items]    
Total Revenues 2,265 2,078
Opdivo Qvantig    
Revenue from External Customer [Line Items]    
Total Revenues 9 0
Orencia    
Revenue from External Customer [Line Items]    
Total Revenues 770 798
Yervoy    
Revenue from External Customer [Line Items]    
Total Revenues 624 583
Reblozyl    
Revenue from External Customer [Line Items]    
Total Revenues 478 354
Opdualag    
Revenue from External Customer [Line Items]    
Total Revenues 252 206
Breyanzi    
Revenue from External Customer [Line Items]    
Total Revenues 263 107
Camzyos    
Revenue from External Customer [Line Items]    
Total Revenues 159 84
Zeposia    
Revenue from External Customer [Line Items]    
Total Revenues 107 110
Abecma    
Revenue from External Customer [Line Items]    
Total Revenues 103 82
Sotyktu    
Revenue from External Customer [Line Items]    
Total Revenues 55 44
Krazati    
Revenue from External Customer [Line Items]    
Total Revenues 48 21
Cobenfy    
Revenue from External Customer [Line Items]    
Total Revenues 27 0
Other Growth products    
Revenue from External Customer [Line Items]    
Total Revenues 403 325
Legacy Portfolio    
Revenue from External Customer [Line Items]    
Total Revenues 5,638 7,073
Eliquis    
Revenue from External Customer [Line Items]    
Total Revenues 3,565 3,720
Revlimid    
Revenue from External Customer [Line Items]    
Total Revenues 936 1,669
Pomalyst/Imnovid    
Revenue from External Customer [Line Items]    
Total Revenues 658 865
Sprycel    
Revenue from External Customer [Line Items]    
Total Revenues 175 374
Abraxane    
Revenue from External Customer [Line Items]    
Total Revenues 105 217
Other Legacy products    
Revenue from External Customer [Line Items]    
Total Revenues $ 199 $ 228