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v3.25.2

ACQUISITIONS, DIVESTITURES, LICENSING AND OTHER ARRANGEMENTS - Narrative (Details) $ / shares in Units, $ in Millions |  |  |  |  | 6 Months Ended | 12 Months Ended | 36 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | ---
May 13, 2025 USD ($) $ / shares | Mar. 18, 2024 USD ($) $ / shares | Feb. 26, 2024 USD ($) $ / shares | Jan. 23, 2024 USD ($) right $ / shares | Jun. 30, 2025 USD ($) | Jun. 30, 2024 USD ($) | Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2026 | Feb. 28, 2025 USD ($)
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Business combination, contingent value, number of rights received | right |  |  |  | 1 |  |  |  |  |  |
Diabetes business - royalties |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Percentage of net sales payable to alliance partner |  |  |  |  | 14.00% |  | 15.00% |  |  |
Philochem |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
License and other arrangements upfront payments |  |  |  |  | $ 350 |  |  |  |  |
Maximum aggregate contingent and regulatory milestone payments |  |  |  |  | 1,000 |  |  |  |  |
BioArctic |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
License and other arrangements upfront payments |  |  |  |  | 100 |  |  |  |  |
Maximum aggregate contingent and regulatory milestone payments |  |  |  |  |  |  |  |  |  | $ 1,300
Keytruda royalties |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Percentage of net sales payable to alliance partner |  |  |  |  |  |  |  | 6.50% |  |
Keytruda royalties | Forecast |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Percentage of net sales payable to alliance partner |  |  |  |  |  |  |  |  | 2.50% |
Keytruda royalties | Forecast | Bristol-Myers Squibb |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Payment and royalty allocation |  |  |  |  |  |  |  |  | 75.00% |
Keytruda royalties | Forecast | Ono |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Payment and royalty allocation |  |  |  |  |  |  |  |  | 25.00% |
RayzeBio |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Share price (in usd per share) | $ / shares |  |  | $ 62.50 |  |  |  |  |  |  |
Total consideration |  |  | $ 4,147 |  |  |  |  |  |  |
Business combination, consideration transferred |  |  | 3,600 |  |  |  |  |  |  |
RayzeBio | Unvested Equity Awards |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Total consideration |  |  | $ 274 |  |  |  |  |  |  |
Mirati Therapeutics |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Share price (in usd per share) | $ / shares |  |  |  | $ 58.00 |  |  |  |  |  |
Total consideration |  |  |  | $ 4,801 |  |  |  |  |  |
Business combination, consideration transferred |  |  |  | $ 4,100 |  |  |  |  |  |
Business combination, contingent value, share price (in dollars per share) | $ / shares |  |  |  | $ 12.00 |  |  |  |  |  |
Continent consideration liability |  |  |  | $ 1,000 |  |  |  |  |  |
Business combination, contingent value payout, period |  |  |  | 7 years |  |  |  |  |  |
2seventy bio |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Asset acquisition, share price (in dollars per share) | $ / shares | $ 5.00 |  |  |  |  |  |  |  |  |
Payments to acquire assets | $ 287 |  |  |  |  |  |  |  |  |
Payments for asset acquisitions, net of cash acquired | $ 114 |  |  |  |  |  |  |  |  |
Karuna |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Asset acquisition, share price (in dollars per share) | $ / shares |  | $ 330.00 |  |  |  |  |  |  |  |
Payments to acquire assets |  | $ 14,027 |  |  |  |  |  |  |  |
Payments for asset acquisitions, net of cash acquired |  | $ 12,900 |  |  |  |  |  |  |  |
Karuna | Acquired IPRD |  |  |  |  |  |  |  |  |  |
Licensing Arrangements [Line Items] |  |  |  |  |  |  |  |  |  |
Payments to acquire assets |  |  |  |  | $ 12,100 | $ 12,100 |  |  |  |

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