<SEC-DOCUMENT>0001415889-22-012339.txt : 20221209
<SEC-HEADER>0001415889-22-012339.hdr.sgml : 20221209
<ACCEPTANCE-DATETIME>20221209170945
ACCESSION NUMBER:		0001415889-22-012339
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20221207
FILED AS OF DATE:		20221209
DATE AS OF CHANGE:		20221209

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Brown Darrell R
		CENTRAL INDEX KEY:			0001727287

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09328
		FILM NUMBER:		221455565

	MAIL ADDRESS:	
		STREET 1:		1 ECOLAB PLACE
		CITY:			ST. PAUL
		STATE:			MN
		ZIP:			55102

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ECOLAB INC.
		CENTRAL INDEX KEY:			0000031462
		STANDARD INDUSTRIAL CLASSIFICATION:	SOAP, DETERGENT, CLEANING PREPARATIONS, PERFUMES, COSMETICS [2840]
		IRS NUMBER:				410231510
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1 ECOLAB PLACE
		CITY:			SAINT PAUL
		STATE:			MN
		ZIP:			55102
		BUSINESS PHONE:		18002326522

	MAIL ADDRESS:	
		STREET 1:		1 ECOLAB PLACE
		CITY:			SAINT PAUL
		STATE:			MN
		ZIP:			55102

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ECOLAB INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ECONOMICS LABORATORY INC
		DATE OF NAME CHANGE:	19861203
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>form4-12092022_101233.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2022-12-07</periodOfReport>

    <issuer>
        <issuerCik>0000031462</issuerCik>
        <issuerName>ECOLAB INC.</issuerName>
        <issuerTradingSymbol>ECL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001727287</rptOwnerCik>
            <rptOwnerName>Brown Darrell R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1 ECOLAB PLACE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PAUL</rptOwnerCity>
            <rptOwnerState>MN</rptOwnerState>
            <rptOwnerZipCode>55102</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>false</isDirector>
            <isOfficer>true</isOfficer>
            <isTenPercentOwner>false</isTenPercentOwner>
            <isOther>false</isOther>
            <officerTitle>PRESIDENT &amp; COO</officerTitle>
            <otherText></otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>20873</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Employee Stock Option (Right to Buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>148.495</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2022-12-07</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>35288</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2023-12-07</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2032-12-07</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>35288</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>35288</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">On February 25, 2022, the reporting person filed a Form 4 reporting the payment of minimum statutory tax obligations incident to the vesting of performance-based restricted stock units in accordance with Rule 16b-3 by withholding 1,166 shares of Ecolab Common Stock. It was later determined that the number of shares withheld was overcounted by 7 shares as a total of 1,159 shares were actually withheld. Accordingly, 7 shares have been added to the reporting person's end of period holdings.</footnote>
        <footnote id="F2">The option will be exercisable, on a cumulative basis, as to one-third of the option shares (excluding any fractional portion less than one share), on each of the first and second anniversaries of the date of grant and as to the remaining shares on the third anniversary of the date of grant. The date listed in the &quot;Date Exercisable&quot; column is the first anniversary of the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ David F. Duvick, as Attorney-in-Fact for Darrell R. Brown</signatureName>
        <signatureDate>2022-12-09</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
