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  <xs:element id="eqix_RestructuringAndRelatedCostsShareBasedPaymentArrangementExpense" abstract="false" name="RestructuringAndRelatedCostsShareBasedPaymentArrangementExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="eqix_RestructuringChargesExcludingShareBasedPaymentArrangementExpense" abstract="false" name="RestructuringChargesExcludingShareBasedPaymentArrangementExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="eqix_NumberOfPrimaryLinesOfBusiness" abstract="false" name="NumberOfPrimaryLinesOfBusiness" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="eqix_AmericasSegmentMember" abstract="true" name="AmericasSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_EMEASegmentMember" abstract="true" name="EMEASegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_AsiaPacificSegmentMember" abstract="true" name="AsiaPacificSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_ColocationMember" abstract="true" name="ColocationMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_InterconnectionMember" abstract="true" name="InterconnectionMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_ManagedInfrastructureMember" abstract="true" name="ManagedInfrastructureMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_OtherMember" abstract="true" name="OtherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_RecurringRevenuesMember" abstract="true" name="RecurringRevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_NonRecurringRevenuesMember" abstract="true" name="NonRecurringRevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_SegmentCostOfRevenue" abstract="false" name="SegmentCostOfRevenue" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="eqix_AdjustedEarningsBeforeInterestTaxesDepreciationAndAmortizationOrAccretion" abstract="false" name="AdjustedEarningsBeforeInterestTaxesDepreciationAndAmortizationOrAccretion" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="eqix_RaoufAbdelMember" abstract="true" name="RaoufAbdelMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_AdaireFoxMartinMember" abstract="true" name="AdaireFoxMartinMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_JonathanLinMember" abstract="true" name="JonathanLinMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_BrandiGalvinMorandiMember" abstract="true" name="BrandiGalvinMorandiMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_KurtPletcherMember" abstract="true" name="KurtPletcherMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_KeithTaylorMember" abstract="true" name="KeithTaylorMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_GrantByGrantBasisMember" abstract="true" name="GrantByGrantBasisMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="eqix_SubjectToPerformanceConditionsMember" abstract="true" name="SubjectToPerformanceConditionsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
