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Supplemental Income Statement Information (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Other (income) expense, net |  |  |
Total Global Growth and Efficiency Program charges, pretax | $ (13) | $ 57 | $ 88
Amortization of intangible assets | 88 | 62 | 59
Equity income | (12) | (9) | (10)
Value-added tax matter in Brazil | 0 | (30) | 0
Write-off of certain investments and fixed assets | 0 | 51 | 1
Acquisition-related costs | 2 | 21 | 0
Charges for a change in go-to-market strategy in certain countries | 0 | 15 | 0
Other, net | 48 | 29 | 10
Total Other (income) expense, net | 113 | 196 | 148
Interest (income) expense, net |  |  |
Interest incurred | 184 | 193 | 195
Interest capitalized | (1) | (1) | (2)
Interest income | (19) | (47) | (50)
Total Interest (income) expense, net | 164 | 145 | 143
Research and development | 290 | 281 | 277
Advertising | $ 1,948 | $ 1,694 | $ 1,590

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