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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Millions | 9 Months Ended
--- | ---
Sep. 30, 2020 | Sep. 30, 2019
Cash flows from operating activities: |  |
Net income | $ 2,364.0 | $ 1,323.8
Adjustments to reconcile net income to net cash provided by operating activities: |  |
Depreciation and amortization | 174.2 | 156.0
Non-cash compensation expense | 310.5 | 330.8
Other non-cash items, net | (111.3) | 113.2
Deferred taxes | 117.9 | (110.0)
Changes in assets and liabilities: |  |
Increase in Sanofi, trade, and other accounts receivable | (1,275.3) | (464.5)
Increase in inventories | (402.4) | (227.2)
Decrease in prepaid expenses and other assets | 16.4 | 24.8
Increase in deferred revenue | 112.3 | 166.8
Increase in accounts payable, accrued expenses, and other liabilities | 80.8 | 328.9
Total adjustments | (976.9) | 318.8
Net cash provided by operating activities | 1,387.1 | 1,642.6
Cash flows from investing activities: |  |
Purchases of marketable and other securities | (2,642.7) | (2,834.9)
Sales or maturities of marketable and other securities | 3,330.3 | 1,306.4
Capital expenditures | (453.2) | (290.6)
Net cash provided by (used in) investing activities | 234.4 | (1,819.1)
Cash flows from financing activities: |  |
Proceeds from issuance of long-term debt | 1,981.9 | 0.0
Proceeds from bridge loan facility | 1,500.0 | 0.0
Repayment of bridge loan facility | (1,500.0) | 0.0
Proceeds from issuance of Common Stock | 2,471.1 | 163.5
Payments in connection with Common Stock tendered for employee tax obligations | (652.5) | (40.5)
Repurchases of Common Stock | (5,465.7) | (29.4)
Net cash (used in) provided by financing activities | (1,665.2) | 93.6
Net decrease in cash, cash equivalents, and restricted cash | (43.7) | (82.9)
Cash, cash equivalents, and restricted cash at beginning of period | 1,630.3 | 1,480.2
Cash, cash equivalents, and restricted cash at end of period | $ 1,586.6 | $ 1,397.3

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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration