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Collaboration Agreements - Amounts Recognized in Statement of Operations with Bayer (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2020 | Sep. 30, 2019 | Sep. 30, 2020 | Sep. 30, 2019
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | $ 2,294.0 | $ 1,743.7 | $ 6,074.2 | $ 4,694.1
Research and development expense | (684.6) | (526.0) | (1,990.5) | (1,897.6)
Bayer | Product and service, other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 299.9 | 293.6 | 825.5 | 834.8
Outside United States | Bayer | Regeneron's net profit in connection with commercialization of EYLEA outside the United States |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 287.9 | 275.0 | 772.6 | 793.3
Outside United States | Bayer | Reimbursement for manufacturing of commercial supplies |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 12.0 | 18.6 | 52.9 | 41.5
Outside United States | Bayer | Reimbursement of development expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Reduction of Research and development expense | 11.5 | 5.0 | 34.3 | 15.6
Outside United States | Bayer | Regeneron's obligation for its share of Bayer research and development expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Research and development expense | (12.9) | (7.0) | (26.3) | (13.6)
Outside United States | Bayer | Reimbursement of other expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Cost of collaboration and contract manufacturing | $ 2.0 | $ 3.7 | $ 5.3 | $ 16.6

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 + Details
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