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Collaboration, License, and Other Agreements - Sanofi, Immuno-Oncology Narrative (Details) - USD ($) $ in Millions |  | 1 Months Ended | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | --- | ---
Jul. 01, 2022 | Jul. 31, 2022 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Dec. 31, 2021
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Revenue milestones |  |  | $ 2,936.2 | $ 3,452.8 | $ 8,758.5 | $ 11,120.0 |
Sanofi |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Up-front payment to collaborating party |  | $ 900.0 |  |  |  |  |
Sanofi Collaboration Agreement, Immuno-oncology |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Royalty payment to collaborating party, percentage of net product sales |  | 11.00% |  |  |  |  |
Other liabilities |  |  | 0.0 |  | $ 0.0 |  | $ 276.1
Sanofi Collaboration Agreement, Immuno-oncology | Amended IO Discovery Agreement | Other operating income |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Cumulative catch-up adjustment to revenue, change in estimate of transaction price |  |  | $ 66.9 |  |  |  |
Sanofi Collaboration Agreement, Immuno-oncology | Regulatory Milestone | Sanofi |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Revenue milestones |  | $ 100.0 |  |  |  |  |
Sanofi Collaboration Agreement, Immuno-oncology | Sales-Based Milestones | Sanofi |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Revenue milestones |  | $ 100.0 |  |  |  |  |
Sanofi Collaboration Agreement, Amended and Restated Immuno-oncology License and Collaboration Agreement |  |  |  |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |  |  |  |
Royalty payment to collaborating party, percentage of net product sales | 0.50% |  |  |  |  |  |
Remaining performance obligation | $ 35.0 |  |  |  |  |  |
Other liabilities | $ 241.0 |  |  |  |  |  |

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