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Collaboration, License, and Other Agreements - Amounts Recognized In Statement of Operations with Sanofi (Details) - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | $ 2,936.2 | $ 3,452.8 | $ 8,758.5 | $ 11,120.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 551.1 | 387.0 | 1,463.0 | 975.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Sales-based milestone earned |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | 50.0 | 50.0 | 50.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Reimbursement for manufacturing of commercial supplies |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 160.5 | 144.7 | 466.8 | 361.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Other |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (0.2) | 0.0 | 28.7 | 0.0
Sanofi Collaboration Agreement, Antibody | (R&D expense)/reduction of R&D expense | (Regeneron's obligation for its share of Sanofi R&D expenses)/reimbursements of R&D expenses, net |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | (4.3) | 34.9 | 59.6 | 89.5
Sanofi Collaboration Agreement, Antibody | Selling, general and administrative expense | Reimbursement of commercialization-related expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 108.6 | 79.0 | 311.1 | 216.9
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization | Outside United States |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | (3.0) | 6.7 | (12.6)
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Reimbursement for manufacturing of ex-U.S. commercial supplies |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | 3.1 | 4.6 | 10.5
Sanofi Collaboration Agreement, Immuno-oncology | (R&D expense)/reduction of R&D expense | Reimbursement of R&D expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | 21.8 | 42.7 | 66.2
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Reimbursement of commercialization-related expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | 22.8 | 41.4 | 62.0
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Regeneron's obligation for its share of Sanofi commercial expenses |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | (9.4) | (19.9) | (28.0)
Sanofi Collaboration Agreement, Immuno-oncology | Cost of goods sold | Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | 0.0 | (34.6) | (70.1) | (99.4)
Sanofi Collaboration Agreement, Immuno-oncology | Other operating income | Amounts recognized in connection with up-front payments received |  |  |  |
Disaggregation of Revenue [Line Items] |  |  |  |
Revenues | $ 0.0 | $ (47.7) | $ 35.1 | $ (4.1)

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