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Commitments and Contingencies - Research Collaboration and Licensing Agreements Narrative (Details) - USD ($) $ in Millions | 1 Months Ended | 12 Months Ended
--- | --- | ---
Aug. 31, 2018 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Libtayo | Sanofi Collaboration Agreement, Immuno-oncology | Through December 31, 2023 |  |  |  |
Research Collaboration and Licensing Arrangements [Line Items] |  |  |  |
Percentage of royalties to be paid | 8.00% |  |  |
Libtayo | Sanofi Collaboration Agreement, Immuno-oncology | January 1, 2024 Through December 31, 2026 |  |  |  |
Research Collaboration and Licensing Arrangements [Line Items] |  |  |  |
Percentage of royalties to be paid | 2.50% |  |  |
Agreements with Royalty Provisions |  |  |  |
Research Collaboration and Licensing Arrangements [Line Items] |  |  |  |
Royalty rate minimum |  | 0.50% |  |
Royalty rate maximum |  | 12.00% |  |
Royalty expense, net of reimbursements from collaborators |  | $ 84.5 | $ 66.9 | $ 56.5

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