| | | | | | | | | | | |
| Name of Subsidiary* | | State or Other Jurisdiction of Incorporation or Organization |
| Checkmate Pharmaceuticals, Inc. | | Delaware |
| Eastside Campus Holdings LLC | | New York |
| Loop Road Holdings LLC | | New York |
| Old Saw Mill Holdings LLC | | New York |
| OSMR Holdings | | Bermuda |
| Regeneron Assurance, Inc. | | New York |
| Regeneron Atlantic Holdings | | Bermuda |
| Regeneron Belgium BV | | Belgium |
| Regeneron Canada Company | | Canada |
| Regeneron Genetics Center LLC | | Delaware |
| Regeneron GmbH | | Germany |
| Regeneron Healthcare Solutions, Inc. | | New York |
| Regeneron India Private Limited | | India |
| Regeneron International Holdings LLC | | Delaware |
| Regeneron Ireland Designated Activity Company | | Ireland |
| Regeneron Japan KK | | Japan |
| Regeneron NL B.V. | | The Netherlands |
| Regeneron Spain, S.L.U. | | Spain |
| Regeneron UK Limited | | United Kingdom |
| Rockwood Road Holdings LLC | | New York |
| _____________ | | |
| * Directly or indirectly wholly owned by Regeneron Pharmaceuticals, Inc. |
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