SEGMENT INFORMATION - Schedule of Expenses by Segment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Segment Reporting Information [Line Items]
Total research and development expense	$ 1,319,775	$ 1,126,232	$ 1,004,415
Total selling, general and administrative expense	1,210,713	975,526	795,646
Compensation and related
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	668,302	531,078	423,295
Consulting and professional services
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	348,976	274,539	226,664
Occupancy and all other costs
Segment Reporting Information [Line Items]
Total selling, general and administrative expense	193,435	169,909	145,687
Clinical research and outside services
Segment Reporting Information [Line Items]
Total research and development expense	640,672	509,129	485,732
Compensation and related
Segment Reporting Information [Line Items]
Total research and development expense	516,208	455,678	357,696
Occupancy and all other costs
Segment Reporting Information [Line Items]
Total research and development expense	$ 162,895	$ 161,425	$ 160,987

The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc.