v3.25.4
Insider Trading Arrangements
3 Months Ended
Dec. 31, 2025
shares
Trading Arrangements, by Individual  
Non-Rule 10b5-1 Arrangement Adopted false
Rule 10b5-1 Arrangement Terminated false
Non-Rule 10b5-1 Arrangement Terminated false
David E.I. Pyott [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
David E.I. Pyott, Director
On November 12, 2025, David E.I. Pyott, a member of our board of directors, entered into a Rule 10b5-1 trading plan that provides that Mr. Pyott, acting through a broker, may sell up to an aggregate of 7,610 shares of our common stock received upon the exercise of options granted to Mr. Pyott as director compensation, subject to adjustments for stock splits, stock combinations, stock dividends and other similar changes to our common stock. Sales of shares under the plan may only occur if the market price of our common stock is above specified prices from February 11, 2026 to October 14, 2026. The plan is scheduled to terminate on October 14, 2026, subject to earlier termination upon the sale of all shares subject to the plan, upon termination by Mr. Pyott or the broker, or as otherwise provided in the plan
Name David E.I. Pyott
Title member of our board of directors
Rule 10b5-1 Arrangement Adopted true
Adoption Date November 12, 2025,
Expiration Date October 14, 2026
Arrangement Duration 245 days
Aggregate Available 7,610
Pushkal Garg, M.D [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
Pushkal Garg, M.D., Chief Research and Development Officer
On November 20, 2025, Pushkal Garg, M.D. our Chief Research and Development Officer, entered into a Rule 10b5-1 trading plan that provides that Dr. Garg, acting through a broker, may sell up to an aggregate of 25,418 shares of our common stock received upon the settlement of awards granted to Dr. Garg as equity incentive compensation, subject to adjustments for stock splits, stock combinations, stock dividends and other similar changes to our common stock. Sales of shares under the plan may only occur from February 27, 2026 to November 1, 2026. The plan is scheduled to terminate on November 1, 2026, subject to earlier termination upon the sale of all shares subject to the plan, upon termination by Dr. Garg or the broker, or as otherwise provided in the plan.
Name Pushkal Garg, M.D
Title Chief Research and Development Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date November 20, 2025
Expiration Date November 1, 2026
Arrangement Duration 247 days
Aggregate Available 25,418
Tolga Tanguler [Member]  
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement
Tolga Tanguler, Chief Commercial Officer
On November 14, 2025, Tolga Tanguler, our Chief Commercial Officer, entered into a Rule 10b5-1 trading plan that provides that Mr. Tanguler, acting through a broker, may sell up to an aggregate of 25,782 shares of our common stock received upon the settlement of awards granted to Mr. Tanguler as equity incentive compensation, subject to adjustments for stock splits, stock combinations, stock dividends and other similar changes to our common stock. Sales of shares under the plan may only occur from February 13, 2026 to November 15, 2026. The plan is scheduled to terminate on November 15, 2026, subject to earlier termination upon the sale of all shares subject to the plan, upon termination by Mr. Tanguler or the broker, or as otherwise provided in the plan.
Name Tolga Tanguler
Title Chief Commercial Officer
Rule 10b5-1 Arrangement Adopted true
Adoption Date November 14, 2025
Expiration Date November 15, 2026
Arrangement Duration 275 days
Aggregate Available 25,782