v3.25.4
LIABILITIES RELATED TO THE SALE OF FUTURE ROYALTIES AND DEVELOPMENT FUNDING (Tables)
 12 Months Ended
Dec. 31, 2025
Related Party Transactions [Abstract]  
Summary of Fair Value, Liabilities
The following table shows the activity with respect to the vutrisiran development funding liability, in thousands:
Carrying value as of January 1, 2025
$190,123 
Interest expense
81,737 
Amount paid
(77,707)
Carrying value as of December 31, 2025
$194,153 
The following table shows the activity with respect to the zilebesiran development funding liability, in thousands:
Carrying value as of January 1, 2025
$25,319 
Interest expense
6,853 
Amount paid
(21,125)
Amount received
6,000 
Carrying value as of December 31, 2025
$17,047 
Schedule of Future Royalties
The following table shows the activity with respect to the liability, in thousands:
Carrying value as of December 31, 2023
$1,377,239 
Interest expense
127,133 
Payments(57,001)
Carrying value as of December 31, 2024
1,447,371 
Interest expense
149,809 
Payments(117,971)
Carrying value as of December 31, 2025
$1,479,209 
Schedule of Development Derivative Liability Activity
The following table presents the activity with respect to the development derivative liability, in thousands:
Carrying value as of December 31, 2023
$324,941 
Amount received under the Development Funding Agreement
12,333 
Amount paid under the Development Funding Agreement
(21,125)
Loss recorded from change in fair value
170,770 
Carrying value as of December 31, 2024
$486,919