INCOME TAXES - Schedule of Components of Net Deferred Tax (Liability) Asset (Detail) - USD ($) $ in Thousands	Dec. 31, 2025	Dec. 31, 2024
Deferred tax assets:
Net operating loss carryforwards	$ 987,117	$ 882,569
Research and development and other credit carryforwards	452,264	391,642
Liabilities related to the sale of future royalties and development funding	426,826	378,657
Change in fair value of development derivative liability	0	107,797
Operating lease liabilities	60,102	60,313
Deferred revenue	1,223	14,515
Deferred compensation	69,981	62,110
Intangible assets	593,725	634,323
Capitalized research and development expenditures	235,622	349,279
Other	90,623	86,425
Total deferred tax assets	2,917,483	2,967,630
Deferred tax liabilities:
Property, plant and equipment, net	(17,367)	(18,596)
Unrealized gain on marketable securities	0	(2,042)
Operating lease right-of-use assets	(41,812)	(41,196)
Deferred tax asset valuation allowance	(2,732,329)	(2,788,933)
Net deferred tax assets	$ 125,975	$ 116,863

Deferred Tax Assets, Capitalized Research and Development Expenditures

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Deferred Tax Assets, Operating Lease Liability

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Deferred Tax Assets, Royalty And Development Funding Liability

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from deferred income.

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 6
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-6

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from derivative instruments.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from intangible assets including goodwill.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences and carryforwards.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
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-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-2

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Amount, after allocation of valuation allowances and deferred tax liability, of deferred tax asset attributable to deductible differences and carryforwards, without jurisdictional netting.

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
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-URI https://asc.fasb.org/1943274/2147482685/740-10-50-2

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards.

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Amount, before allocation of valuation allowance, of deferred tax asset attributable to deductible temporary differences, classified as other.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible research tax credit carryforwards.

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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible temporary differences from compensation and benefits costs.

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Amount of deferred tax assets for which it is more likely than not that a tax benefit will not be realized.

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Amount of deferred tax liability attributable to taxable temporary differences from leasing arrangements.

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Amount of deferred tax liability attributable to taxable temporary differences from unrealized gains in other comprehensive income.

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Amount of deferred tax liability attributable to taxable temporary differences from property, plant, and equipment.

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