    <SEC-DOCUMENT>0001140361-26-013365-index.html : 20260406
    <SEC-HEADER>0001140361-26-013365.hdr.sgml : 20260406
    <ACCEPTANCE-DATETIME>20260406170120
    ACCESSION NUMBER:		0001140361-26-013365
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260406
    DATE AS OF CHANGE:		20260406
    EFFECTIVENESS DATE:		20260406

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ALNYLAM PHARMACEUTICALS, INC.
    		CENTRAL INDEX KEY:			0001178670
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				770602661
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36407
    		FILM NUMBER:		26841993

    	BUSINESS ADDRESS:
    		STREET 1:		675 WEST KENDALL STREET
    		STREET 2:		HENRI A. TERMEER SQUARE
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142
    		BUSINESS PHONE:		(617) 551-8200

    	MAIL ADDRESS:
    		STREET 1:		675 WEST KENDALL STREET
    		STREET 2:		HENRI A. TERMEER SQUARE
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ALNYLAM PHARMACEUTICALS INC
    		DATE OF NAME CHANGE:	20020724
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ef20069834_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: ef20069834_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>