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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Schedule of Earnings Before Income Taxes
Earnings before income taxes for the years ended December 31, 2021, 2020 and 2019 consisted of the following components:

 202120202019
United States$915.3 $752.7 $1,741.2 
Other355.7 298.7 316.2 
 $1,271.0 $1,051.4 $2,057.4 
Schedule of Components of Income Tax Expense (Benefit)
Components of income tax expense for the years ended December 31, 2021, 2020 and 2019 were as follows:

 202120202019
Current:   
Federal$130.6 $157.5 $366.5 
State56.8 50.0 72.0 
Foreign94.5 75.3 77.9 
Deferred:   
Federal28.0 (56.7)(47.1)
State(26.6)(5.2)(2.2)
Foreign5.1 5.0 (49.7)
 $288.4 $225.9 $417.4 
Schedule of Effective Income Tax Rate Reconciliation
Reconciliations between the statutory federal income tax rate and the effective income tax rate for the years ended December 31, 2021, 2020 and 2019 were as follows:

 202120202019
Federal statutory rate21.0 %21.0 %21.0 %
Foreign operations, net2.6 1.7 (0.1)
R&D tax credits(1.8)(1.4)(0.5)
State taxes, net of federal benefit2.7 2.9 1.4 
Stock-based compensation(2.3)(3.3)(1.3)
Impact of UK tax rate change1.7 — — 
Divestitures— — 2.0 
Legal entity restructuring(1.2)— (2.0)
Other, net— 0.6 (0.2)
 22.7 %21.5 %20.3 %
Schedule of Deferred Tax Assets and Liabilities
Components of the deferred tax assets and liabilities at December 31 were as follows:

 20212020
Deferred tax assets:  
Reserves and accrued expenses$195.8 $175.0 
Net operating loss carryforwards101.5 153.6 
R&D credits12.5 26.2 
Interest expense limitation carryforwards10.9 63.0 
Outside basis differences on assets held for sale57.5 — 
Lease liability52.6 56.3 
Valuation allowance(44.4)(37.7)
Total deferred tax assets$386.4 $436.4 
Deferred tax liabilities:  
Reserves and accrued expenses$16.1 $21.5 
Amortizable intangible assets1,670.2 1,762.8 
Plant and equipment3.8 7.4 
Accrued tax on unremitted foreign earnings24.7 18.6 
ROU asset50.0 54.4 
Total deferred tax liabilities$1,764.8 $1,864.7 
Schedule of Unrecognized Tax Benefits Roll Forward
A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows:

 202120202019
Beginning balance$75.6 $69.8 $63.6 
Additions for tax positions of prior periods2.2 6.0 2.9 
Additions for tax positions of the current period3.3 3.5 4.2 
Additions due to acquisitions1.0 6.2 1.9 
Reductions for tax positions of prior periods(0.6)(3.6)(0.3)
Reductions attributable to lapses of applicable statute of limitations(4.6)(6.3)(2.5)
Reductions attributable to settlements with taxing authorities(27.5)— — 
Ending balance$49.4 $75.6 $69.8