<SEC-DOCUMENT>0001086888-18-000061.txt : 20180509
<SEC-HEADER>0001086888-18-000061.hdr.sgml : 20180509
<ACCEPTANCE-DATETIME>20180509111019
ACCESSION NUMBER:		0001086888-18-000061
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20180509
FILED AS OF DATE:		20180509
DATE AS OF CHANGE:		20180509

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MANULIFE FINANCIAL CORP
		CENTRAL INDEX KEY:			0001086888
		STANDARD INDUSTRIAL CLASSIFICATION:	LIFE INSURANCE [6311]
		IRS NUMBER:				889897526
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14942
		FILM NUMBER:		18817241

	BUSINESS ADDRESS:	
		STREET 1:		200 BLOOR ST EAST, NT-10
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M4W1E5
		BUSINESS PHONE:		416-926-3000

	MAIL ADDRESS:	
		STREET 1:		200 BLOOR ST EAST, NT-10
		CITY:			TORONTO
		STATE:			A6
		ZIP:			M4W1E5
</SEC-HEADER>
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<TYPE>6-K
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<DESCRIPTION>FORM6-K-9MAY2018-5THSUPPLINDENT
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<div style="TEXT-ALIGN: center; FONT: bold 14pt/13.7pt 'Times New Roman Bold', serif">SECURITIES AND EXCHANGE COMMISSION</div>

<div style="TEXT-ALIGN: center; FONT: bold 12pt/15.95pt 'Times New Roman', serif">Washington, D.C. 20549</div>

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<font style="FONT-VARIANT: normal; FONT-STYLE: normal; FONT-SIZE: 12pt; FONT-WEIGHT: bold">REPORT OF <font style="FONT-FAMILY: 'Times New Roman Bold', serif">FOREIGN</font> PRIVATE ISSUER PURSUANT TO RULE 13<font style="FONT-FAMILY: 'Times New Roman Bold', serif">a</font>-16 OR <font style="FONT-FAMILY: 'Times New Roman Bold', serif">15d</font>-16 UNDER THE</font></div>

<div style="TEXT-ALIGN: center; FONT: bold 12pt/13.7pt 'Times New Roman', serif">SECURITIES EXCHANGE ACT OF 1934</div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">For the month of <font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>May, 2018.</u></font></div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">Commission File Number: 1-14942</div>

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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 15.95pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 14pt; FONT-WEIGHT: bold"><font style="FONT-VARIANT: normal; FONT-STYLE: normal; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 16pt; FONT-WEIGHT: bold">MANULIFE FINANCIAL CORPORATION</font>

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<div style="TEXT-ALIGN: center; FONT: 10pt/11.4pt 'Times New Roman', serif">(Translation of registrant's name into English)</div>

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<div style="TEXT-ALIGN: center; FONT: bold 12pt/15.95pt 'Times New Roman', serif">200 Bloor Street East</div>

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<div style="TEXT-ALIGN: center; FONT: bold 12pt/15.95pt 'Times New Roman', serif">Toronto, Ontario, Canada M4W 1E5</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form&#160;40-F.</div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): <font style="FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 11pt">&#9744;</font></div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): <font style="FONT-FAMILY: 'Times New Roman', Times, serif; FONT-SIZE: 11pt">&#9744;</font></div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934.</div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: normal">If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2(b): 82- ________.</div>

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<div style="TEXT-ALIGN: center; FONT: bold 12pt/13.7pt 'Times New Roman', serif">DOCUMENTS FILED AS PART OF THIS FORM 6-K</div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Fifth Supplemental Indenture dated May 9, 2018 between Manulife Financial Corporation and BNY Trust Company of Canada</div>
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<div style="TEXT-ALIGN: left; TEXT-INDENT: 36pt; FONT: 11pt/12.55pt 'Times New Roman', serif">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.</div>

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<div style="TEXT-ALIGN: left; FONT: 14pt/15.95pt 'Times New Roman', serif">MANULIFE FINANCIAL CORPORATION</div>
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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">By:&#160;&#160;&#160;&#160;&#160;&#160; </font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">/s/</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">&#160;</font><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Kay Song</font></font></div>
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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Name:&#160; </font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Kay Song</font></div>
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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; TEXT-INDENT: -36.6pt; MARGIN-LEFT: 36.6pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Title:&#160;&#160;&#160; </font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Assistant Corporate Secretary</font></div>
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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Date:&#160; May 9, 2018</div>
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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Fifth Supplemental Indenture dated May 9, 2018 between Manulife Financial Corporation and BNY Trust Company of Canada`</div>
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<TYPE>EX-99.1
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<DESCRIPTION>EXHIBIT99-1-9MAY2018-5THSUPPLINDENT
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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">MANULIFE FINANCIAL CORPORATION</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">and</div>

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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 24pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">as TRUSTEE</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">FIFTH SUPPLEMENTAL INDENTURE</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Supplemental to</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">THE TRUST INDENTURE</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">MADE AS OF MAY 25, 2016</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">and providing for the issue of</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">$600,000,000</font>&#160;<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">PRINCIPAL AMOUNT OF 3.317% FIXED/FLOATING</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><br>
</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">SUBORDINATED DEBENTURES</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><br>
</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">due</font><a name="_mps388865350000000000000004379000000000"><!--Anchor--></a><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"> May 9, 2028</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><br>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">THIS FIFTH SUPPLEMENTAL INDENTURE made as of May 9, 2018</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">BETWEEN:</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 72pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">MANULIFE FINANCIAL CORPORATION</font>, a corporation existing under the <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Insurance Companies Act </font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">(</font>Canada) and having its registered office in the City of Toronto in the Province of Ontario</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 72pt; FONT-SIZE: 11pt">(the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Corporation</font>"),</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 72pt; FONT-SIZE: 11pt">- and -</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 72pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">BNY TRUST COMPANY OF CANADA</font>, a trust company incorporated under the federal laws of Canada and having an office in the City of Toronto in the Province of Ontario</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 72pt; FONT-SIZE: 11pt">(the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Trustee</font>")</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS </font>by a trust indenture made as of May 25, 2016 (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Principal Indenture</font>") between the Corporation and the Trustee, provision was made for the issue in series of subordinated unsecured debentures; and</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> by a First Supplemental Indenture (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">First Supplemental Indenture</font>") made as of May 25, 2016 between the Corporation, the Trustee, The Bank of New York Mellon, London Branch as principal paying agent and calculation agent (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Principal Paying Agent and Calculation Agent</font>") and the Bank of New York Mellon SA/NV, Luxembourg Branch as registrar and transfer agent (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Registrar and Transfer Agent</font>"), provision was made for the issue of a series of debt securities in Singapore, such series being the 3.85% Subordinated Notes due May 25, 2026 in the aggregate principal amount of S$500,000,000, upon the terms set forth in the Principal Indenture as supplemented by the First Supplemental Indenture; and</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> by a Second Supplemental Indenture (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Second Supplemental Indenture</font>") made as of July 27, 2017 between the Corporation and the Trustee, amendment was made to the Principal Indenture to, among other things, amend the application of certain sections; and</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> by a Third Supplemental Indenture (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Third Supplemental Indenture</font>") made as of August 15, 2017 between the Corporation and the Trustee, provision was made for the issue of a series of debt securities in Canada, such series being the 3.049% Fixed/Floating Subordinated Debentures due August 20, 2029 in the aggregate principal amount of $750,000,000, upon the terms set forth in the Principal Indenture as supplemented by the Second Supplemental Indenture and the Third Supplemental Indenture; and</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> by a Fourth Supplemental Indenture (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Fourth Supplemental Indenture</font>") made as of November 21, 2017 between the Corporation, the Trustee, the Principal Paying Agent and Calculation Agent and the Registrar and Transfer Agent, provision was made for the issue of a series of debt securities in Singapore, such series being the 3.00% Subordinated Notes due November 21, 2029 in the aggregate principal amount of S$500,000,000, upon the terms set forth in the Principal Indenture as supplemented by the Second Supplemental Indenture and the Fourth Supplemental Indenture; and</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> the Corporation is duly authorized to create and issue a series of debt securities upon the terms set forth in the Principal Indenture. The terms, provisions and conditions of such series are provided for by the Second Supplemental Indenture and this Fifth Supplemental Indenture which supplement the Principal Indenture, such series being the 3.317% Fixed/Floating Subordinated Debentures due May 9, 2028 in an aggregate principal amount of $600,000,000 (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Debentures</font>"). In connection therewith, the Corporation has requested that the Trustee execute this Fifth Supplemental Indenture; and</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS</font> all necessary corporate action has been taken by the Corporation to make the Debentures, when certified by the Trustee and issued as provided in this Fifth Supplemental Indenture, valid, binding and legal obligations of the Corporation with the benefit and subject to the terms of the Principal Indenture as supplemented by the Second Supplemental Indenture and this Fifth Supplemental Indenture; and</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">WHEREAS </font>the terms of this Fifth Supplemental Indenture are to be executed and delivered by the parties hereto by way of supplement to the Principal Indenture in order to provide for the issue of the Debentures; and</div>

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</font> INTERPRETATION</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><u>To be read with Principal Indenture.</u></div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Fifth Supplemental Indenture and the Second Supplemental Indenture are integral to the Principal Indenture and shall hereafter be read together with the Principal Indenture and shall have effect as if all the provisions thereof and hereof were contained in one instrument.</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><u>Definitions.</u></div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">In this Fifth Supplemental Indenture, unless there is something in the subject matter or context inconsistent therewith:</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">the expressions "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Article</font>" and "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Section</font>" followed by a number mean and refer to the specified Article and Section of this Fifth Supplemental Indenture unless otherwise expressly stated. Other expressions defined in the Principal Indenture have the same meanings when used in this Fifth Supplemental Indenture.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">3-month CDOR</font>" means, for any quarterly floating rate interest period, the average bid rate of interest (expressed as an annual percentage rate) rounded to the nearest one-hundred-thousandth of 1.00% (with .000005 per cent being rounded up) for Canadian dollar bankers' acceptances with maturities of three months which appears on the Reuters Screen CDOR Page as of 10:00 a.m., Toronto time, on the first Business Day of such quarterly interest period; provided that if such rate does not appear on the Reuters Screen </div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">CDOR Page on such day or if the Reuters Monitor Money Rates Service is not available or ceases to exist, the 3-month CDOR for such period will be determined using an Alternative CDOR Page as of an Alternative Time on such day. If no such Alternative CDOR Page is available on such day, the 3-month CDOR for such period shall be the average of the bid rates of interest (expressed and rounded as set forth above) for Canadian dollar bankers' acceptances with maturities of three months for same day settlement as quoted by such of the Schedule I banks (as defined in the Bank Act (Canada)) as may quote such a rate as of 10:00 a.m., Toronto time, on the first Business Day of such quarterly interest period.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Alternative CDOR Page</font>" shall mean the display designated as page "CDOR" on Bloomberg or an equivalent service that displays average bid rates of interest for Canadian dollar bankers' acceptances with maturities of three months.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Alternative Time</font>", for any Alternative CDOR Page, shall mean the time of day at which such Alternative CDOR Page becomes available.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Business Day</font>" means any day on which Canadian chartered banks are open for business in Toronto and which is not a Saturday or Sunday.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Debentures</font>" means the debentures of the series referred to in <a href="#_Ref305758504">Article&#160;2</a> of this Fifth Supplemental Indenture.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Indenture</font>" (when not qualified by the words "Principal", "Original" or "Supplemental"), "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">hereto</font>", "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">hereby</font>", "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">hereunder</font>", "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">hereof</font>", "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">herein</font>" and similar expressions refer to the Principal Indenture as supplemented by the Second Supplemental Indenture and this Fifth Supplemental Indenture and not to any particular Article, Section, subdivision or portion hereof.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">LICAT</font>" means the Life Insurance Capital Adequacy Test (or any successor or replacement capital requirements applicable to the Corporation) for Canadian federally regulated life insurance companies.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 12pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Program Amount</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">" means the aggregate principal amount of debentures qualified for issuance from time to time under the Prospectus then in effect. As of the date of this Fifth Supplemental Indenture the Program Amount is $10,000,000,000.</font></div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Prospectus</font>" means the short form base shelf prospectus of the Corporation with respect to the continuous offering of debentures filed with the securities regulatory authority in each of the provinces and territories of Canada from time to time, including any amendments or supplements thereto (other than any Prospectus Supplement).</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Prospectus Supplement</font>" means a prospectus supplement for the Debentures.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Reuters Screen CDOR Page</font>" means the display designated as page "CDOR" on the Reuters Monitor Money Rates Service (or such other page as may replace the CDOR page on that service) for purposes of displaying Canadian dollar bankers' acceptance rates.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">U.S. Securities Act</font>" means the United States <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Securities Act of 1933</font>, as amended.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Written Order of the Corporation</font>" has the meaning given in the Principal Indenture.</div>
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</font><a name="_Ref307733237"><!--Anchor--></a>ISSUE OF SUBORDINATED DEBENTURES</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><u>Form, Terms and Certification and Delivery of the 3.317% Fixed/Floating Subordinated Debentures.</u></div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">The fourth series of debentures authorized to be issued from time to time hereunder, as one series, are designated "3.317% Fixed/Floating Subordinated Debentures" and are herein sometimes called the "Debentures". The Debentures may be issued by the Corporation from time to time in an unlimited aggregate principal amount and may only be validly issued when the aggregate principal amount of the Debentures to be issued, when added to the aggregate principal amount of all debentures previously or simultaneously issued under the Prospectus in effect on the date of issue, does not exceed the Program Amount. Upon any increase or decrease from time to time in the Program Amount, the Corporation shall forthwith deliver to the Trustee a certified copy of the resolution of the Directors of the Corporation approving such change, together with a copy of any amendment of or supplement to the Prospectus relating to such increase or decrease. Debentures shall be delivered to the Trustee on the respective terms set out in <a href="#_Ref307733260">Article&#160;4</a> and, subject to compliance with the provisions of Section 2.2.1 of the Principal Indenture, shall be certified by or on behalf of the Trustee by a certificate substantially in the form specified on Schedule A and delivered by the Trustee upon receipt of the Written Order of the Corporation.</div>
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</font><a name="_Ref307737423"><!--Anchor--></a>TERMS OF THE DEBENTURES</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">In accordance with the Principal Indenture the Corporation is authorized to issue under this Fifth Supplemental Indenture the 3.317% Fixed/Floating Subordinated Debentures as a series of debt securities, which will have the respective terms set out in this <a href="#_Ref307737423">Article&#160;3</a> in addition to the terms set out in the Principal Indenture as supplemented by the Second Supplemental Indenture.</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Principal Amount.</font> The initial principal amount of the Debentures which may be issued under this Fifth Supplemental Indenture is $600,000,000. The Corporation may, at its option, reopen this series of debt securities in accordance with the provisions of Section 2.2.3 of the Principal Indenture.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Issue Date</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Debentures will be dated May 9, 2018 (regardless of their actual date of issue) (the "<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Issue Date</font>").</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Fixed Rate of Interest. </font>The Debentures will bear interest from the Issue Date to but excluding May 9, 2023 at a fixed annual rate of 3.317% payable in equal semi-annual installments on May 9 and November 9 of each year, with the first interest payment due on November 9, 2018 and the last interest payment due on May 9, 2023.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Floating Rate of Interest. </font>The Debentures will bear interest from and including May 9, 2023 to but excluding May 9, 2028, at a floating rate of interest equal to the 3-month CDOR plus 0.78% payable quarterly in arrears on the 9th day of each of February, May, August and November in each year, commencing August 9, 2023. The Corporation shall provide to the Trustee its interest calculation in respect of any floating rate interest period.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Calculation of Interest. </font>Interest will be calculated on the basis of a year of 365 days.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Stated Maturity Date</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Debentures will mature on May 9, 2028.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Denominations</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Debentures will be issued in minimum denominations of $1,000 and integral multiples thereof, subject as provided in accordance with clause <a href="#_Ref305757876">(k)</a> below.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Redemptions</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Corporation may, at its option, redeem the Debentures, with the prior approval of the Superintendent, in accordance with the provisions of Article 3 of the Principal Indenture and on not less than 30 days' nor more than 60 days' prior notice to the applicable Holder, in whole or in part, on or after May 9, 2023 at a redemption price equal to par, together with accrued and unpaid interest to but excluding the date of redemption.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Defeasance.</font> On or after<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">&#160;</font>May 9, 2023, the Corporation may, at its option, elect, with the prior approval of the Superintendent, to be released from the terms of the Indenture relating to the outstanding Debentures in accordance with the provisions of Article 8 of the Principal Indenture.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Amendments Affecting Capital Treatment.</font> Each of the Corporation and the Trustee agrees, and each Holder of a Debenture, by such Holder's acceptance thereof, likewise agrees, not to make any changes to this Indenture or the Debentures, without, but may from time to time with, the prior approval of the Superintendent, which might affect the classification afforded the Debentures from time to time for capital adequacy purposes pursuant to the <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Insurance Companies Act</font> (Canada) or the LICAT.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Currency</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Debentures will be issued in Canadian Dollars.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Form</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> Each Debenture will be issued substantially in the form of the registered Debenture as set out in <a href="#_Ref305757950">Article&#160;4</a>.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">Place of Payment</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> Payments of principal and interest on each registered interest bearing Debenture shall be made in Canadian Dollars at the head office of the Trustee in Toronto, Ontario.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">U.S. Legend</font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">.</font> The Trustee acknowledges that the Debentures have not been and will not be registered under the U.S. Securities Act, and may not be offered or sold within the United States, except that the Debentures may be offered or sold to Qualified Institutional</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Buyers pursuant to Rule 144A under the U.S. Securities Act. Each Debenture issued to a U.S. Person pursuant to an exemption from the registration requirements of the U.S. Securities Act, and all Debentures issued in exchange or transfer therefor, shall bear the legend set forth on Schedule B in boldface print on the face of such certificate.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Upon receipt by the Trustee of the documents and instruments required pursuant to Section 2.5.1 of the Indenture and this Fifth Supplemental Indenture, the Trustee shall certify the Debentures and cause the Debentures to be delivered in accordance with the Written Order of the Corporation.</div>
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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><u>Execution and Delivery of Book-Entry Securities.</u></div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The Corporation may establish that any Debentures are to be issued under the Book-Entry System in accordance with Section 2.15 of the Principal Indenture, which Book-Entry Debentures shall be evidenced in the form of a single Definitive Security in the form set out in <a href="#_Ref305757950">Article&#160;4</a> and shall bear a legend substantially to the following effect:</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>Interest Act</u></font><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u> Disclosure Matters.</u></font></div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">Subject to the terms of the Indenture, the Corporation understands and acknowledges that it is able to calculate the rate of interest applicable to the Debentures under the Indenture based on the methodology for calculating per annum rates provided for under Section 2.6.5 of the Principal Indenture. The Trustee, or applicable calculation agent, agrees that if requested in writing by the Corporation it will calculate the nominal and effective per annum rate of interest on the Debentures outstanding at the time of such request and provide such information to the Corporation promptly following such request; provided that any error in any such calculation, or any failure to provide such information on request, shall not relieve the Corporation of any of its obligations under the Indenture, nor result in any liability to the Trustee or calculation agent. The Corporation confirms that it agrees not to plead or assert, whether by way of defence or otherwise, in any proceeding relating to the Indenture, that the interest payable under the Debentures and the calculation thereof has not been adequately disclosed to the Corporation, whether pursuant to Section 4 of the <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Interest Act</font> (Canada) or any other applicable law or legal principle.</div>

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</font><a name="_Ref307733260"><!--Anchor--></a>FORM OF 3.317% FIXED/FLOATING SUBORDINATED DEBENTURES</div>

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<div style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"><u>3.317% Fixed/Floating Subordinated Debentures.</u></div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The English language version of the Definitive Securities representing the Debentures, the certificate of the Trustee and the registration panel for a Debenture shall be substantially in the respective forms set forth in Schedule A modified as may be necessary to reflect the specific terms and conditions of the Debentures determined in accordance with <a href="#_Ref307737423">Article&#160;3</a>.</div>

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</font> SUNDRY PROVISIONS</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The Trustee hereby accepts the trusts in this Fifth Supplemental Indenture declared and provided for and agrees to perform the same upon the terms and conditions and subject to the provisions set forth in the Indenture. This agreement and all documents relating to the transactions covered hereby have been drawn up in English at the express wish of the parties. <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Ce contrat et tous les documents pertinents &#225; cette transaction ont &#233;t&#233; r&#233;dig&#233;s en anglais &#225; la volont&#233; expresse des parties</font>.</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 72pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Fifth Supplemental Indenture may be executed in several counterparts and delivered by facsimile or other electronic transmission, each of which so executed shall be deemed to be an original, and such counterparts together shall be deemed to bear the same date as the Issue Date.</div>

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<div style="LINE-HEIGHT: 12.55pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">IN WITNESS WHEREOF</font> the parties hereto have executed this Fifth Supplemental Indenture as of the Issue Date specified above.</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">"Halina K. von dem Hagen"</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">Certificate No.&#160;1</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">Unless this certificate is presented by an authorized representative of CDS Clearing and Depository Services Inc. ("CDS") to Manulife Financial Corporation (the "Issuer") or its agent for registration of transfer, exchange or payment, and any certificate issued in respect thereof is registered in the name of CDS &amp; CO., or in such other name as is requested by an authorized representative of CDS (and any payment is made to CDS &amp; CO. or to such other entity as is requested by an authorized representative of CDS), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered holder hereof, CDS &amp; CO., has a property interest in the securities represented by this certificate herein and it is a violation of its rights for another person to hold, transfer or deal with this certificate.</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">THIS DEBENTURE CONSTITUTES SUBORDINATED INDEBTEDNESS OF THE CORPORATION</div>

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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">MANULIFE FINANCIAL CORPORATION</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(Existing under the<font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"> Insurance Companies Act</font> (Canada)),</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">May 9, 2018</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">CDS &amp; Co.</div>
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<div style="LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">$600,000,000</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">3.317% (0 - 5 years); 3-month CDOR + 0.78% (5<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold"> </font>years - maturity)</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: normal; FONT-FAMILY: 'Times New Roman', serif; LETTER-SPACING: normal; FONT-SIZE: 11pt">May 9 and November 9 (0 - 5 years, commencing on November 9, 2018); February 9, May 9, August 9 and November 9 in each year, commencing on August 9, 2023 (5 years - maturity)</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">MANULIFE FINANCIAL CORPORATION</font> (the "Corporation") for value received hereby acknowledges itself indebted and promises to pay to the Holder hereof on the maturity date or on such earlier or later date as the principal amount hereof may become due in accordance with the provisions of the Indenture hereinafter mentioned, the above principal sum in lawful money of Canada on presentation and surrender of this Debenture at the head office of the Trustee (as defined below), if this instrument is issued in the book-entry system, or at any branch in Canada of the Royal Bank of Canada, as selected by the Holder, if this instrument is issued in definitive form, as selected by the Holder, and to pay interest on the principal amount hereof from the date hereof, or from the last Interest Payment Date to which interest has been paid or made available for payment, whichever is later, at the interest rate per annum set forth above calculated as set forth above, in like money; and should the Corporation at any time make default in the payment of any principal or interest, to pay interest on the amount in default at the same rate, calculated as set forth above, in like money, at one of the said places, as selected by the Holder, and on the same dates. Whenever interest is computed on a basis of a year (the "deemed year") which contains fewer days than the actual number of days in the calendar year of calculation, such rate of interest shall be expressed as a yearly rate for purposes of the <font style="FONT-STYLE: italic; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Interest Act</font> (Canada) by multiplying such rate of such interest by the actual number of days in the calendar year of calculation and dividing it by the number of days in the deemed year.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Debenture is one of the debentures of the Corporation, issued or issuable in one series under the provisions of the Trust Indenture made as of May 25, 2016 (the "Principal Indenture") as supplemented by the Second Supplemental Indenture made as of July 27, 2017 and the Fifth Supplemental Indenture</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">made as of May 9, 2018 (collectively, the "Indenture") between the Corporation and BNY Trust Company of Canada (the "Trustee"). Reference is hereby expressly made to the Indenture for particulars of the rights of the Holders of the Debentures and of the Corporation and of the Trustee in respect thereof and the terms and conditions upon which the Debentures are issued or may be issued and held, all to the same effect as if the provisions of the Indenture were herein set forth, to all of which provisions the Holder of this Debenture by acceptance hereof assents. Capitalized terms used but not defined herein have the meanings attributed to them in the Indenture. The 3.317% Fixed/Floating Subordinated Debentures due May 9, 2028 (the "Debentures"), of which this is one, are issuable by the Corporation from time to time in an unlimited aggregate principal amount, subject to the terms and conditions of the Indenture. The aggregate principal amount of debentures of other series which may be issued under the Indenture is unlimited, but such debentures may be issued only upon the terms and subject to the conditions provided in the Indenture.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The indebtedness evidenced by this Debenture and all other debentures now or hereafter certified and delivered under the Indenture is subordinated and subject in right of payment, to the extent and in the manner provided in the Indenture, to the prior payment of all Senior Indebtedness (as defined in the Indenture) and all Policy Liabilities (as defined in the Indenture) of the Corporation, whether outstanding at the date of the Indenture or thereafter created, incurred, assumed or guaranteed.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The Debentures are direct obligations of the Corporation but are not secured by any mortgage, pledge, hypothec or other charge.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">As interest on this Debenture becomes due, the Corporation (except in the case of payment at maturity or on acceleration or redemption, at which time payment of interest may be made upon surrender of this Debenture) shall, at least three business days prior to each date on which interest becomes due, forward or cause to be forwarded by (i) electronic transfer of immediately available funds to the account designated by the applicable Holder, or (ii) first class mail, postage prepaid, to the Holder hereof, or in the case of joint Holders, to the joint Holder whose name first appears on the register, subject to the provisions of the Indenture and in the manner provided therein, a cheque for such interest, in each case less any tax required by law to be deducted. Subject to the provisions of the Indenture, the transfer of such funds or the mailing of such cheque shall satisfy and discharge all liability for interest on this Debenture to the extent of the sum represented by such cheque (plus the amount of any tax withheld).</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">Upon compliance with the provisions of the Indenture, Debentures of any denomination may be exchanged for an equal aggregate principal amount of Debentures in any other authorized denomination or denominations.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The right is reserved to the Corporation to purchase or redeem Debentures for cancellation in accordance with the provisions of the Indenture.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The principal hereof may become or be declared due and payable before the stated maturity date in the events, in the manner, with the effect and at the times provided in the Indenture.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The Indenture contains provisions making binding upon all Holders of Debentures outstanding thereunder resolutions passed at meetings of such Holders held in accordance with such provisions and instruments signed by the Holders of a specified majority of such Debentures outstanding.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Debenture has not been and will not be registered under the United States Securities Act of 1933, as amended (the "U.S. Securities Act") or any state securities laws and may not be offered, sold or delivered, directly or indirectly, in the United States of America, its territories, its possessions and other areas subject to its jurisdiction or to, or for the account or benefit of a U.S. person (as defined in Regulation S</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">under the U.S. Securities Act) except in certain transactions exempt from the registration requirements of the U.S. Securities Act and applicable state securities laws.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Debenture may only be transferred, upon compliance with the conditions prescribed in the Indenture, in one of the registers to be kept at the principal office of the Trustee in the City of Toronto by the Holder hereof or such Holder's executors or administrator or other legal representatives, or such Holder's attorney duly appointed by an instrument in form and substance satisfactory to the Trustee or other registrar, and upon compliance with such reasonable requirements as the Trustee and/or other registrar may prescribe.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">The Indenture and the Debentures shall be governed by, and construed in accordance with, the laws of the Province of Ontario and the laws of Canada applicable therein.</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Name:&#160; Philip J. Witherington</div>
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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(FORM OF TRUSTEE'S CERTIFICATE)</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">TRUSTEE'S CERTIFICATE</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">This Definitive Security represents one of the Debentures of a series of 3.317% Fixed/Floating Subordinated Debentures referred to in the Indenture within mentioned.</div>

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<div style="TEXT-ALIGN: left; LINE-HEIGHT: 12.55pt; MARGIN-TOP: 2pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 24pt; FONT-SIZE: 11pt">Trustee</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">By:</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Name:&#160;&#160; Bret S. Derman<font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><br>
</font> Title:&#160; &#160;&#160;&#160; Authorized Signatory</div>
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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(FORM OF REGISTRATION PANEL)</div>

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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(No writing hereon except by the Trustee or other registrar)</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt; FONT-WEIGHT: bold">&#160;Signature of Trustee or Registrar</div>
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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(FORM OF CERTIFICATE OF TRANSFER)</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">CERTIFICATE OF TRANSFER</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">To assign this Debenture, fill in the form below:</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">I or we assign and transfer this Debenture to</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(Print or type assignee's name, address and postal code)</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">(Insert assignee's social insurance or security or tax identifying number)</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">and irrevocably appoint _______________ agent to transfer this Debenture on the books of the Corporation. The agent may substitute another to act for him.</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; MARGIN-TOP: 12pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Date:</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 25.1pt; MARGIN-TOP: 12pt; FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt">Your Signature:</div>
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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 6pt; FONT-SIZE: 11pt">Sign exactly as your name appears on the other side of this Debenture.</div>

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<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; TEXT-INDENT: 288pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 6pt; FONT-SIZE: 11pt">* Signature Guarantee</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 36pt; FONT-SIZE: 11pt">* This signature must be guaranteed by a Canadian chartered bank, trust company or a member of the Investment Industry Regulatory Organization of Canada.</div>

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<div style="TEXT-ALIGN: center; LINE-HEIGHT: 13.7pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 12pt">SCHEDULE B</div>

<div style="TEXT-ALIGN: center; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt; FONT-WEIGHT: bold">FORM OF U.S. LEGEND</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; FONT-SIZE: 11pt">THE SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR THE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES. THE HOLDER HEREOF, BY PURCHASING SUCH SECURITIES, AGREES FOR THE BENEFIT OF MANULIFE FINANCIAL CORPORATION (THE "CORPORATION") THAT SUCH SECURITIES MAY BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED, DIRECTLY OR INDIRECTLY, ONLY (A) TO THE CORPORATION, (B) OUTSIDE THE UNITED STATES IN ACCORDANCE WITH RULE 904 OF REGULATION S UNDER THE SECURITIES ACT AND IN COMPLIANCE WITH LOCAL LAWS AND REGULATIONS OR (C) INSIDE THE UNITED STATES IN ACCORDANCE WITH (1) RULE 144A UNDER THE SECUR1TIES ACT OR (2) RULE 144 UNDER THE SECURITIES ACT, IF AVAILABLE, AND, IN EACH CASE, IN COMPLIANCE WITH APPLICABLE STATE SECURITIES LAWS. IN THE CASE OF (C) ABOVE, THE HOLDER MUST FURNISH TO THE CORPORATION AN OPINION OF COUNSEL OF RECOGNIZED STANDING IN FORM AND SUBSTANCE REASONABLY SATISFACTORY TO THE CORPORATION TO THE EFFECT THAT THE PROPOSED TRANSFER MAY BE EFFECTED WITHOUT REGISTRATION UNDER THE SECURITIES ACT OR APPLICABLE STATE SECURITIES LAWS. IF THE CORPORATION IS A "FOREIGN ISSUER" WITHIN THE MEANING OF REGULATION S AT THE TIME OF TRANSFER, A NEW CERTIFICATE, BEARING NO LEGEND, DELIVERY OF WHICH WILL CONSTITUTE "GOOD DELIVERY", MAY BE OBTAINED FROM THE TRUST COMPANY (THE "TRUSTEE") UPON DELIVERY OF THIS CERTIFICATE AND A DULY EXECUTED DECLARATION IN A FORM SATISFACTORY TO THE TRUSTEE AND THE CORPORATION, TO THE EFFECT THAT THE SALE OF THE SECURITIES REPRESENTED HEREBY IS BEING MADE IN COMPLIANCE WITH RULE 904 OF REGULATION S UNDER THE SECURITIES ACT;</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 36pt; FONT-SIZE: 11pt"><font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>provided</u></font>, that if the Debentures are being sold under Clause (B), the legend may be removed by providing a declaration to the Trustee, to the following effect (or in such form as the Corporation or the Trustee may from time to time prescribe):</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 36pt; FONT-SIZE: 11pt">The undersigned (A) acknowledges that the sale of <font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>&#160; &#160;&#160; </u></font>Debentures, represented by certificate numbers <font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>&#160; &#160; &#160; &#160;&#160; &#160;</u></font>, to which this declaration relates is being made in reliance upon Rule 904 of Regulation S under the United States Securities Act of 1933 (the "Securities Act") and (B) certifies that (1) it is not an "affiliate" of Manulife Financial Corporation (as defined in Rule 405 under the Securities Act), (2) the offer of such securities was not made to a person in the United States and at the time the buy order was originated, the buyer was outside the United States, or the seller and any person acting on its behalf reasonably believe that the buyer was outside the United States and neither the seller nor any person acting on its behalf knows that the transaction has been prearranged with a buyer in the United States, (3) neither the seller nor any person acting on its behalf engaged or will engage in any directed selling efforts in connection with the offer and sale of such securities, and (4) the contemplated sale is not a transaction, or part of a series of transactions which, although in technical compliance with Regulation S, is part of a plan or scheme to evade the registration provisions of the Securities Act. Terms used herein have the meaning given to them by Regulation S.</div>

<div style="TEXT-ALIGN: justify; LINE-HEIGHT: 12.55pt; FONT-FAMILY: 'Times New Roman', serif; MARGIN-BOTTOM: 12pt; MARGIN-LEFT: 36pt; FONT-SIZE: 11pt">and, <font style="FONT-FAMILY: 'Times New Roman', serif; FONT-SIZE: 11pt"><u>provided further</u></font>, that if any such securities are being sold under paragraph (C)(2) above the legend may be removed by delivery to the Trustee of an opinion of counsel, of recognized standing reasonably satisfactory to the Corporation, that such legend is no longer required under applicable requirements of the Securities Act or state securities laws.</div>

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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
