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INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Schedule of Income Before Provisions for Income Taxes
The Company's income before provision for income taxes was generated from operations in the United States and outside of the United States as follows (in millions):
 Years Ended December 31,
 202120202019
United States$610.9 $151.3 $383.4 
Outside of the United States, including Puerto Rico1,091.1 765.4 783.1 
$1,702.0 $916.7 $1,166.5 
Schedule of Provision for Income Taxes
The provision for income taxes consists of the following (in millions):
 Years Ended December 31,
 202120202019
Current   
United States:   
Federal$125.2 $23.4 $31.3 
State and local25.1 48.2 48.7 
Outside of the United States, including Puerto Rico92.6 73.9 29.1 
Current income tax expense$242.9 $145.5 $109.1 
Deferred   
United States:   
Federal$(9.4)$11.0 $28.3 
State and local(25.4)(32.9)(18.3)
Outside of the United States, including Puerto Rico(9.2)(30.3)0.5 
Deferred income tax (benefit) expense(44.0)(52.2)10.5 
Total income tax provision$198.9 $93.3 $119.6 
Schedule of Deferred Tax Assets and Liabilities
The components of deferred tax assets and liabilities are as follows (in millions):
 December 31,
 20212020
Deferred tax assets  
Compensation and benefits$109.8 $88.6 
Benefits from uncertain tax positions33.9 27.0 
Net tax credit carryforwards142.0 125.5 
Net operating loss carryforwards69.4 64.1 
Accrued liabilities108.0 105.0 
Inventories13.5 16.3 
Cash flow and net investment hedges— 3.3 
State income taxes0.4 0.5 
Investments0.7 1.8 
Lease liability obligations6.6 7.7 
Other1.3 3.6 
Total deferred tax assets485.6 443.4 
Deferred tax liabilities  
Property, plant, and equipment(64.1)(53.4)
Cash flow and net investment hedges(6.4)— 
Deferred tax on foreign earnings(26.3)(29.2)
Right-of-use assets (6.1)(7.0)
Other intangible assets(75.5)(76.3)
Other(2.6)(3.1)
Total deferred tax liabilities(181.0)(169.0)
Valuation allowance(82.5)(71.6)
Net deferred tax assets$222.1 $202.8 
Schedule of Net Operating Loss Carryforwards
Net operating loss and capital loss carryforwards and the related carryforward periods at December 31, 2021 are summarized as follows (in millions):
 Carryforward
Amount
Tax Benefit
Amount
Valuation
Allowance
Net Tax
Benefit
Carryforward
Period Ends
United States federal net operating losses$17.6 $3.7 $— $3.7 2030-2037
United States federal net operating losses11.3 2.4 — 2.4 Indefinite
United States state net operating losses33.5 1.6 (1.6)— 2026-2039
United States state net operating losses1.0 0.1 (0.1)— Indefinite
Non-United States net operating losses5.8 1.5 (1.2)0.3 2022-2028
Non-United States net operating losses353.3 60.1 (50.8)9.3 Indefinite
United States capital losses34.1 0.2 (0.2)— 2024
Total$456.6 $69.6 $(53.9)$15.7  
Schedule of Tax Credit Carryforwards
The gross tax credit carryforwards and the related carryforward periods at December 31, 2021 are summarized as follows (in millions):
 Carryforward
Amount
Valuation
Allowance
Net Tax
Benefit
Carryforward
Period Ends
California research expenditure tax credits$167.0 $— $167.0 Indefinite
Federal research expenditure tax credits1.5 — 1.5 2026-2039
Foreign tax credits2.9 (2.9)— 2030-2031
Puerto Rico purchases credit23.4 (23.4)— Indefinite
Total$194.8 $(26.3)$168.5  
Reconciliation of Federal Statutory Income Tax Rate to Effective Income Tax Rate
A reconciliation of the United States federal statutory income tax rate to the Company's effective income tax rate is as follows (in millions):
 Years Ended December 31,
 202120202019
Income tax expense at United States federal statutory rate$357.4 $192.5 $245.0 
Foreign income taxed at different rates(122.2)(80.5)(75.0)
State and local taxes, net of federal tax benefit11.9 5.0 11.9 
Tax credits, federal and state(48.4)(43.1)(42.9)
Build of reserve for prior years' uncertain tax positions3.6 4.2 5.0 
Tax on global intangible low-taxed income56.5 49.2 32.0 
Foreign-derived intangible income deduction(1.3)(2.6)(7.2)
Contingent consideration liabilities(26.1)2.9 (1.3)
United States federal deductible employee share-based compensation(47.8)(48.3)(57.6)
Nondeductible employee share-based compensation5.3 4.2 3.2 
Other10.0 9.8 6.5 
Income tax provision$198.9 $93.3 $119.6 
Reconciliation of Beginning and Ending Amount of Uncertain Tax Positions
A reconciliation of the beginning and ending amount of uncertain tax positions, excluding interest, penalties, and foreign exchange, is as follows (in millions):
 December 31,
 202120202019
Uncertain gross tax positions, January 1$281.8 $203.1 $150.7 
Current year tax positions
82.1 86.4 55.4 
Increase in prior year tax positions
2.3 6.0 0.8 
Decrease in prior year tax positions
(4.8)(10.0)(3.8)
Settlements
(0.3)(3.7)— 
Lapse of statutes of limitations
(2.7)— — 
Uncertain gross tax positions, December 31$358.4 $281.8 $203.1