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<!--XBRL Document Created with the Workiva Platform-->
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<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
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  <link:roleRef roleURI="http://www.xbrl.org/2009/role/netLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/net-2009-12-16.xsd#netLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedNetLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedNetLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTerseLabel"/>
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  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedLabel"/>
  <link:roleRef roleURI="http://www.xbrl.org/2009/role/negatedTotalLabel" xlink:type="simple" xlink:href="http://www.xbrl.org/lrr/role/negated-2009-12-16.xsd#negatedTotalLabel"/>
  <link:labelLink xlink:role="http://www.xbrl.org/2003/role/link" xlink:type="extended">
    <link:label id="lab_ew_MichaelMussallemMember_label_en-US" xlink:label="lab_ew_MichaelMussallemMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Michael Mussallem [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_ew_MichaelMussallemMember" xlink:href="ew-20250325.xsd#ew_MichaelMussallemMember"/>
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    <link:label id="lab_ew_WoodMember_label_en-US" xlink:label="lab_ew_WoodMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Wood [Member]</link:label>
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    <link:loc xlink:type="locator" xlink:label="loc_ew_ZovighianMember" xlink:href="ew-20250325.xsd#ew_ZovighianMember"/>
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    <link:label id="lab_ew_LemercierMember_label_en-US" xlink:label="lab_ew_LemercierMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lemercier [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_ew_LemercierMember" xlink:href="ew-20250325.xsd#ew_LemercierMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ew_LemercierMember" xlink:to="lab_ew_LemercierMember" xlink:type="arc" order="1"/>
    <link:label id="lab_ew_ChopraMember_label_en-US" xlink:label="lab_ew_ChopraMember" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Chopra [Member]</link:label>
    <link:loc xlink:type="locator" xlink:label="loc_ew_ChopraMember" xlink:href="ew-20250325.xsd#ew_ChopraMember"/>
    <link:labelArc xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_ew_ChopraMember" xlink:to="lab_ew_ChopraMember" xlink:type="arc" order="1"/>
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