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Income Taxes - Tax Provision And Effective Tax Rate (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Amount      
Provision for income taxes at statutory federal income tax rate $ 111,025    
State income taxes, net of federal income tax effect 955    
Stock-based compensation (285,955)    
Research and development credits (57,630)    
Change in valuation allowance 172,418    
Non-deductible compensation 69,402    
Other non-taxable or non-deductible items 1,299    
Return to provision true-ups (6,317)    
Other 251    
Income tax expense (benefit) $ (1,031) $ (931) $ 3,801
Percent      
Provision for income taxes at statutory federal income tax rate 21.00% 21.00% 21.00%
State income taxes, net of federal benefit 0.20% 5.30% 1.20%
Stock-based compensation (54.10%)    
Other   (0.20%) (2.90%)
Research and development credits (10.90%) 14.60% 13.50%
Change in valuation allowance 32.60% (71.00%) (41.10%)
Non-deductible compensation 0.131 (0.140) 0
Other non-taxable or non-deductible items 0.30%    
Return to provision true-ups (1.20%)    
Other 0.00%    
Effective tax rate (0.20%) 0.10% (4.40%)
UNITED KINGDOM      
Amount      
Stock-based compensation $ (5,851)    
Other $ (698)    
Percent      
Stock-based compensation (1.10%)    
Other (0.10%)    
Other foreign jurisdictions      
Amount      
Other foreign jurisdictions $ 70    
Percent      
Other foreign jurisdictions 0.00%