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Property, Plant and Equipment, Net - Construction in Progress (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Property and equipment |  |
Construction in progress | $ 654,018 | $ 740,615
Building |  |
Property and equipment |  |
Construction in progress | 528,629 | 579,649
Manufacturing equipment |  |
Property and equipment |  |
Construction in progress | 89,897 | 119,380
Laboratory equipment |  |
Property and equipment |  |
Construction in progress | 9,805 | 16,135
Other |  |
Property and equipment |  |
Construction in progress | $ 25,687 | $ 25,451

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- Definition Amount of structure or a modification to a structure under construction. Includes recently completed structures or modifications to structures that have not been placed into service. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 360 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482099/360-10-50-1 + Details
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