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Supplemental Balance Sheet Information - Schedule of Accrued Expenses and Other Payables (Details) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Accrued expenses and other payables |  |
Compensation related | $ 248,348 | $ 217,803
Sales rebates and returns related | 235,600 | 139,936
External research and development activities related | 154,269 | 162,969
Commercial activities | 77,530 | 87,572
Accrued general and administrative expenses | 31,106 | 36,203
Individual income tax and other taxes | 34,904 | 30,083
Other | 21,956 | 19,165
Total | $ 803,713 | $ 693,731

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- Definition Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received and amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer. + References No definition available. + Details
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- Definition Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 210 -SubTopic 10 -Name Accounting Standards Codification -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(20)) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480566/210-10-S99-1 + Details
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