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Supplemental Balance Sheet Information
 12 Months Ended
Dec. 31, 2024
Balance Sheet Related Disclosures [Abstract]  
Supplemental Balance Sheet Information Supplemental Balance Sheet Information
Prepaid expenses and other current assets consist of the following:
 As of December 31,
 20242023
 $$
Prepaid research and development costs64,277 60,476 
Prepaid taxes23,792 37,320 
Other receivables32,828 37,859 
Prepaid general and administrative expenses21,253 14,619 
Prepaid manufacturing cost19,333 42,066 
Short-term restricted cash9,312 11,473 
Prepaid insurance6,242 8,872 
Other current assets 15,882 44,780 
Total192,919 257,465 
Other non-current assets consist of the following:
 As of December 31, 
 20242023
 $$
Long-term investments128,933 89,644 
Prepaid supply cost12,249 18,122 
Rental deposits and other8,481 8,195 
Prepayment of property and equipment5,927 4,144 
Prepaid VAT2,875 2,546 
Long-term restricted cash2,025 2,711 
Total160,490 125,362 
Accrued expenses and other payables consisted of the following:
 As of December 31, 
 20242023
 $$
Compensation related248,348 217,803 
Sales rebates and returns related235,600 139,936 
External research and development activities related154,269 162,969 
Commercial activities77,530 87,572 
Accrued general and administrative expenses31,106 36,203 
Individual income tax and other taxes34,904 30,083 
Other21,956 19,165 
Total803,713 693,731 
Other long-term liabilities consist of the following:
 As of December 31, 
 20242023
 $$
Deferred government grant income30,324 34,204 
Pension liability16,405 14,995 
Asset retirement obligation3,794 1,127 
Other16,212 484 
Total66,735 50,810