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Collaborative and Licensing Arrangements - Financing Liability (Details) - Amgen, Inc - USD ($)
$ in Thousands
Dec. 31, 2024
Dec. 31, 2023
Research and Development Arrangement, Contract to Perform for Others    
Research and development cost share liability, current portion $ 111,154 $ 68,004
Research and development cost share liability, non-current portion 54,286 170,662
Total research and development cost share liability $ 165,440 $ 238,666