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Collaborative and Licensing Arrangements - Amounts and Classification of Payments (Income/(Expense) (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Research and Development Arrangement, Contract to Perform for Others
Total	$ (48,962)	$ (50,871)	$ (50,183)
Accounts payable	404,997	315,111
Amgen, Inc | Collaborative Arrangement
Research and Development Arrangement, Contract to Perform for Others
Collaborative arrangement, inventory purchases	247,655	108,691	71,720
Amgen, Inc | Collaborative Arrangement | Related Party
Research and Development Arrangement, Contract to Perform for Others
Accounts payable	116,563	55,474
Cost of sales - product
Research and Development Arrangement, Contract to Perform for Others
Total	37,150	8,358	5,898
Selling, General and Administrative Expense
Research and Development Arrangement, Contract to Perform for Others
Total	(83,674)	(60,917)	(54,865)
Research and development
Research and Development Arrangement, Contract to Perform for Others
Total	$ (2,438)	$ 1,688	$ (1,216)

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