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CONSOLIDATED STATEMENTS OF SHAREHOLDERS’ EQUITY - USD ($)
$ in Thousands
Total
Ordinary Shares
Additional Paid-In Capital
Accumulated Other Comprehensive Income/(Loss)
Accumulated Deficit
Balance at the beginning of period (in shares) at Dec. 31, 2021   1,334,804,281      
Balance at the beginning of period at Dec. 31, 2021 $ 6,132,563 $ 133 $ 11,191,007 $ 17,950 $ (5,076,527)
Increase (Decrease) in Stockholders' Equity          
Cost from issuance of ordinary shares $ (152)   (152)    
Issuance of shares reserved for share option exercises (in shares) 5,898,217 1,375,621      
Exercise of options, ESPP and release of RSUs (in shares)   19,960,278      
Exercise of options, ESPP and release of RSUs $ 46,964 $ 2 46,962    
Share-based compensation 303,162   303,162    
Other comprehensive loss (95,367)     (95,367)  
Net loss (2,003,815)       (2,003,815)
Balance at the ending of period (in shares) at Dec. 31, 2022   1,356,140,180      
Balance at the ending of period at Dec. 31, 2022 $ 4,383,355 $ 135 11,540,979 (77,417) (7,080,342)
Increase (Decrease) in Stockholders' Equity          
Issuance of shares reserved for share option exercises (in shares) 6,974,331 84,227      
Exercise of options, ESPP and release of RSUs (in shares)   26,561,925      
Exercise of options, ESPP and release of RSUs $ 53,008 $ 2 53,006    
Share-based compensation 367,618   367,618    
Cancellation of ordinary shares (in share)   (23,273,108)      
Cancellation of ordinary shares   $ (2) (362,915)    
Other comprehensive loss (22,029)     (22,029)  
Net loss $ (881,708)       (881,708)
Balance at the ending of period (in shares) at Dec. 31, 2023 1,359,513,224 1,359,513,224      
Balance at the ending of period at Dec. 31, 2023 $ 3,537,327 $ 135 11,598,688 (99,446) (7,962,050)
Increase (Decrease) in Stockholders' Equity          
Issuance of shares reserved for share option exercises (in shares) 6,812,624 (2,258,161)      
Exercise of options, ESPP and release of RSUs (in shares)   30,112,641      
Exercise of options, ESPP and release of RSUs $ 45,553 $ 3 45,550    
Deconsolidation of a subsidiary 2,052   2,052    
Share-based compensation 441,618   441,618    
Cancellation of ordinary shares (362,917)        
Other comprehensive loss (49,542)     (49,542)  
Net loss $ (644,786)       (644,786)
Balance at the ending of period (in shares) at Dec. 31, 2024 1,387,367,704 1,387,367,704      
Balance at the ending of period at Dec. 31, 2024 $ 3,332,222 $ 138 $ 12,087,908 $ (148,988) $ (8,606,836)