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Income Taxes - Significant Components of Deferred Tax Assets (Liabilities) (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Deferred Tax Assets, Net [Abstract]
Accruals and reserves	$ 121,549	$ 106,708	$ 97,896
Net operating losses carryforward	1,137,890	996,588	862,214
Stock-based compensation	38,397	26,687	19,700
Research tax credits	34,561	68,117	86,000
Tax relief credits	704,928	704,928	0
Intangible asset amortization	1,081,442	699,974	813,043
Lease liability obligation	11,882	7,893	10,348
R&D and other capitalized costs	277,061	164,190	63,156
Total gross deferred tax assets	3,407,710	2,775,085	1,952,357
Less valuation allowance	(3,403,505)	(2,771,470)	(1,943,775)	$ (1,758,409)
Net deferred tax assets	4,205	3,615	8,582
Property, plant and equipment, net	(10,795)	(12,374)	(14,480)
Tax on unremitted earnings	(23,735)	0	0
Right of use asset	(11,682)	(7,735)	(10,098)
Total gross deferred tax liabilities	(46,212)	(20,109)	(24,578)
Net deferred tax assets/(liabilities)	$ (42,007)	$ (16,494)	$ (15,996)

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