<SEC-DOCUMENT>0000093751-25-000088.txt : 20250205
<SEC-HEADER>0000093751-25-000088.hdr.sgml : 20250205
<ACCEPTANCE-DATETIME>20250205074955
ACCESSION NUMBER:		0000093751-25-000088
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250205

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			REGENXBIO Inc.
		CENTRAL INDEX KEY:			0001590877
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				471851754
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-89108
		FILM NUMBER:		25590931

	BUSINESS ADDRESS:	
		STREET 1:		9804 MEDICAL CENTER DRIVE
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850
		BUSINESS PHONE:		240-552-8181

	MAIL ADDRESS:	
		STREET 1:		9804 MEDICAL CENTER DRIVE
		CITY:			ROCKVILLE
		STATE:			MD
		ZIP:			20850

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	REGENXBIO, Inc.
		DATE OF NAME CHANGE:	20150116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ReGenX Biosciences, LLC
		DATE OF NAME CHANGE:	20131101

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			STATE STREET CORP
		CENTRAL INDEX KEY:			0000093751
		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
		ORGANIZATION NAME:           	02 Finance
		IRS NUMBER:				042456637
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		1 CONGRESS STREET
		STREET 2:		SUITE 1
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02114
		BUSINESS PHONE:		617 786-3000

	MAIL ADDRESS:	
		STREET 1:		1 CONGRESS STREET
		STREET 2:		SUITE 1
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02114

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STATE STREET Corp
		DATE OF NAME CHANGE:	20090218

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STATE STREET CORP
		DATE OF NAME CHANGE:	19970424

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STATE STREET BOSTON FINANCIAL CORP
		DATE OF NAME CHANGE:	19780525
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
   <headerData>
      <submissionType>SCHEDULE 13G</submissionType>
      <filerInfo>
         <filer>
            <filerCredentials>
               <cik>0000093751</cik>
               <ccc>XXXXXXXX</ccc>
            </filerCredentials>
         </filer>
         <liveTestFlag>LIVE</liveTestFlag>



      </filerInfo>
   </headerData>
   <formData>
      <coverPageHeader>
         <securitiesClassTitle>COMMON STOCK</securitiesClassTitle>
         <eventDateRequiresFilingThisStatement>12/31/2024</eventDateRequiresFilingThisStatement>
         <issuerInfo>
            <issuerCik>0001590877</issuerCik>
            <issuerName>REGENXBIO INC</issuerName>
            <issuerCusip>75901B107</issuerCusip>
            <issuerPrincipalExecutiveOfficeAddress>
               <com:street1>9804 MEDICAL CENTER DR   </com:street1>
               <com:city>ROCKVILLE</com:city>
               <com:stateOrCountry>MD</com:stateOrCountry>
               <com:zipCode>20850</com:zipCode>
            </issuerPrincipalExecutiveOfficeAddress>
         </issuerInfo>
         <designateRulesPursuantThisScheduleFiled>
            <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
         </designateRulesPursuantThisScheduleFiled>
      </coverPageHeader>
      <coverPageHeaderReportingPersonDetails>


         <reportingPersonName>STATE STREET CORPORATION</reportingPersonName>
         <citizenshipOrOrganization>MA</citizenshipOrOrganization>
         <reportingPersonBeneficiallyOwnedNumberOfShares>
            <soleVotingPower>0.00</soleVotingPower>
            <sharedVotingPower>2035671.00</sharedVotingPower>
            <soleDispositivePower>0.00</soleDispositivePower>
            <sharedDispositivePower>2185851.00</sharedDispositivePower>
         </reportingPersonBeneficiallyOwnedNumberOfShares>
         <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>2185851.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
         <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
         <classPercent>4.4</classPercent>
         <typeOfReportingPerson>HC</typeOfReportingPerson>
      </coverPageHeaderReportingPersonDetails>
      <items>
         <item1>
            <issuerName>REGENXBIO INC</issuerName>
            <issuerPrincipalExecutiveOfficeAddress>9804 MEDICAL CENTER DR , ROCKVILLE, MARYLAND, 20850</issuerPrincipalExecutiveOfficeAddress>
         </item1>
         <item2>
            <filingPersonName>STATE STREET CORPORATION;</filingPersonName>
            <principalBusinessOfficeOrResidenceAddress>ONE CONGRESS STREET, SUITE 1, BOSTON MA 02114, UNITED STATES</principalBusinessOfficeOrResidenceAddress>
            <citizenship>MA</citizenship>
         </item2>
         <item3>
            <notApplicableFlag>N</notApplicableFlag>
            <typeOfPersonFiling>IA</typeOfPersonFiling>
            <typeOfPersonFiling>HC</typeOfPersonFiling>
         </item3>
         <item4>
            <amountBeneficiallyOwned>2185851.00</amountBeneficiallyOwned>
            <classPercent>4.4</classPercent>
            <numberOfSharesPersonHas>
               <solePowerOrDirectToVote>0</solePowerOrDirectToVote>
               <sharedPowerOrDirectToVote>2,035,671</sharedPowerOrDirectToVote>
               <solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
               <sharedPowerOrDirectToDispose>2,185,851</sharedPowerOrDirectToDispose>
            </numberOfSharesPersonHas>
         </item4>
         <item5>
            <notApplicableFlag>N</notApplicableFlag>
            <classOwnership5PercentOrLess>Y</classOwnership5PercentOrLess>
         </item5>
         <item6>
            <notApplicableFlag>N</notApplicableFlag>
            <ownershipMoreThan5PercentOnBehalfOfAnotherPerson>NOT APPLICABLE</ownershipMoreThan5PercentOnBehalfOfAnotherPerson>
         </item6>
         <item7>
            <notApplicableFlag>N</notApplicableFlag>
            <subsidiaryIdentificationAndClassification>SSGA FUNDS MANAGEMENT, INC. (IA);STATE STREET GLOBAL ADVISORS EUROPE LIMITED (IA);STATE STREET GLOBAL ADVISORS LIMITED (IA);STATE STREET GLOBAL ADVISORS TRUST COMPANY (IA);STATE STREET GLOBAL ADVISORS, LTD. (IA);</subsidiaryIdentificationAndClassification>
         </item7>
         <item8>
            <notApplicableFlag>N</notApplicableFlag>
            <identificationAndClassificationOfGroupMembers>NOT APPLICABLE</identificationAndClassificationOfGroupMembers>
         </item8>
         <item9>
            <notApplicableFlag>N</notApplicableFlag>
            <groupDissolutionNotice>NOT APPLICABLE</groupDissolutionNotice>
         </item9>
         <item10>
            <notApplicableFlag>N</notApplicableFlag>
            <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
         </item10>
      </items>
      <signatureInformation>
         <reportingPersonName>STATE STREET CORPORATION</reportingPersonName>
         <signatureDetails>
            <signature>ELIZABETH SCHAEFER</signature>
            <title>SENIOR VICE PRESIDENT, CHIEF ACCOUNTING OFFICER</title>
            <date>01/31/2025</date>
         </signatureDetails>
      </signatureInformation>
   </formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
