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Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2015

Summary of Significant Accounting Policies

Reconciliation of the weighted average number of shares used to compute basic and diluted net loss per share

		Years Ended December 31,
		2015			2014			2013
		(In thousands, except per share amounts)
Numerator:
Net loss:		$	(118,183	)	$	(79,159	)	$	(56,073	)
​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​	​	​	​
Denominator:
Weighted average common shares used in calculation of basic net loss per share:			58,633			43,095			34,980
Effect of dilutive securities:
Common stock options			-			-			-
Restricted stock and restricted stock units			-			-			-
Common stock warrant			-			-			-
​	​	​	​	​	​	​	​	​	​	​
Weighted average common shares outstanding used in calculation of diluted net loss per share			58,633			43,095			34,980
​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​	​	​	​
Net loss per share:
Basic and Diluted		$	(2.02	)	$	(1.84	)	$	(1.60	)
​	​	​	​	​	​	​	​	​	​	​
​	​	​	​	​	​	​	​	​	​	​

Potentially dilutive securities excluded from computations of diluted weighted-average shares outstanding

              The following potentially dilutive securities have been excluded from the computations of diluted weighted-average common shares outstanding as of December 31, 2015, 2014 and 2013 as their effect would have been anti-dilutive (in thousands).

		2015			2014			2013
Stock options to purchase common stock			5,274			4,400			3,633
Restricted stock and restricted stock units			44			21			93

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- Definition

Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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- Definition

Tabular disclosure of the weighted average number of shares used in calculating basic net earnings per share (or unit) and diluted earnings per share (or unit).

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 260
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257

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