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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Warrant
Additional Paid-in Capital
Accumulated Deficit
Total
Balance at Dec. 31, 2012 $ 315 $ 790 $ 455,325 $ (335,548) $ 120,882
Balance (in shares) at Dec. 31, 2012 31,488,000 330,000      
Comprehensive loss:          
Net loss       (56,073) (56,073)
Exercise of stock options $ 4   1,622   $ 1,626
Exercise of stock options (in shares) 372,000       371,743
Net proceeds from issuance of common stock $ 69   66,948   $ 67,017
Net proceeds from issuance of common stock (in shares) 6,900,000        
Issuance of common stock for vesting of RSUs $ 1   (1)    
Issuance of common stock for vesting of RSUs (in shares) 154,000        
Exercise of warrants $ 2 $ (790) 788    
Exercise of warrants (in shares) 223,000 (330,000)      
Reclass of stock compensation expense for liability awards to equity     3,371   3,371
Stock compensation expense     6,501   6,501
Balance at Dec. 31, 2013 $ 391   534,554 (391,621) 143,324
Balance (in shares) at Dec. 31, 2013 39,137,000        
Comprehensive loss:          
Net loss       (79,159) (79,159)
Exercise of stock options $ 3   1,728   $ 1,731
Exercise of stock options (in shares) 283,000       283,057
Net proceeds from issuance of common stock $ 103   108,910   $ 109,013
Net proceeds from issuance of common stock (in shares) 10,306,000        
Issuance of common stock for vesting of RSUs $ 1   (1)    
Issuance of common stock for vesting of RSUs (in shares) 80,000        
Stock compensation expense     11,328   11,328
Balance at Dec. 31, 2014 $ 498   656,519 (470,780) 186,237
Balance (in shares) at Dec. 31, 2014 49,806,000        
Comprehensive loss:          
Net loss       (118,183) (118,183)
Exercise of stock options $ 5   5,107   $ 5,112
Exercise of stock options (in shares) 481,000       481,140
Net proceeds from issuance of common stock $ 115   222,827   $ 222,942
Net proceeds from issuance of common stock (in shares) 11,500,000        
Issuance of common stock for vesting of RSUs (in shares) 27,000        
Stock compensation expense     15,590   15,590
Balance at Dec. 31, 2015 $ 618   $ 900,043 $ (588,963) $ 311,698
Balance (in shares) at Dec. 31, 2015 61,814,000