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Intangibles, net (Details) - USD ($) $ in Thousands |  | 12 Months Ended |  |
--- | --- | --- | --- | ---
Sep. 28, 2018 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Jan. 01, 2018 | Jan. 01, 2017
Goodwill and Intangible Assets Disclosure [Abstract] |  |  |  |  |  |
New drug milestone payment | $ 1,700 | $ 1,724 | $ 0 | $ 0 |  |
Intangibles, net |  | $ 58,675 | 58,200 |  |  |
Intangible assets estimated useful life |  | 12 years |  |  |  |
Amortization of intangible assets, 2019 |  | $ 5,000 |  |  |  |
Amortization of intangible assets, 2020 |  | 5,000 |  |  |  |
Amortization of intangible assets, 2021 |  | 5,000 |  |  |  |
Amortization of intangible assets, 2022 |  | 5,000 |  |  |  |
Amortization of intangible assets, 2023 |  | 5,000 |  |  |  |
Finite-lived Intangible Assets [Roll Forward] |  |  |  |  |  |
Intangibles, gross |  |  |  |  | $ 58,200 | $ 58,200
Additions |  | 1,724 | 0 |  |  |
Amortization |  | (1,249) | 0 |  |  |
Intangibles, net |  | 58,675 | 58,200 |  |  |
In Process Research and Development |  |  |  |  |  |
Goodwill and Intangible Assets Disclosure [Abstract] |  |  |  |  |  |
Intangibles, net |  | 56,988 | 58,200 |  |  |
Finite-lived Intangible Assets [Roll Forward] |  |  |  |  |  |
Intangibles, gross |  |  |  |  | 58,200 | $ 58,200
Additions |  | 0 | 0 |  |  |
Amortization |  | (1,212) | 0 |  |  |
Intangibles, net |  | 56,988 | $ 58,200 |  |  |
Licensing Agreements |  |  |  |  |  |
Goodwill and Intangible Assets Disclosure [Abstract] |  |  |  |  |  |
Intangibles, net |  | 1,687 |  |  |  |
Finite-lived Intangible Assets [Roll Forward] |  |  |  |  |  |
Intangibles, gross |  |  |  |  | $ 0 |
Additions |  | 1,724 |  |  |  |
Amortization |  | (37) |  |  |  |
Intangibles, net |  | $ 1,687 |  |  |  |

X
- Definition Useful life of finite-lived intangible assets, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References No definition available. + Details
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