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Fixed Assets, net (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Property, Plant and Equipment
Fixed assets, gross	$ 36,809	$ 23,077
Less accumulated depreciation	(14,173)	(10,645)
Fixed assets, net	22,636	12,432
Depreciation expense	3,600	2,900	$ 2,400
Depreciation increase (decrease)	10,200
Lab equipment
Property, Plant and Equipment
Fixed assets, gross	$ 7,935	7,055
Estimated Useful Life (years)	7 years
Furniture and fixtures
Property, Plant and Equipment
Fixed assets, gross	$ 2,320	1,937
Estimated Useful Life (years)	7 years
Computer hardware and software
Property, Plant and Equipment
Fixed assets, gross	$ 3,796	2,325
Computer hardware and software | Minimum
Property, Plant and Equipment
Estimated Useful Life (years)	3 years
Computer hardware and software | Maximum
Property, Plant and Equipment
Estimated Useful Life (years)	5 years
Office equipment
Property, Plant and Equipment
Fixed assets, gross	$ 65	65
Estimated Useful Life (years)	7 years
Manufacturing equipment
Property, Plant and Equipment
Fixed assets, gross	$ 1,166	1,436
Estimated Useful Life (years)	7 years
Leasehold improvements
Property, Plant and Equipment
Fixed assets, gross	$ 7,202	6,939
Construction in progress (CIP)
Property, Plant and Equipment
Fixed assets, gross	14,325	$ 3,320
Depreciation increase (decrease)	$ 11,000

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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