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Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2020

Accounting Policies [Abstract]

Schedule of Carrying Value and Fair Value of Assets and Liabilities

The following table shows assets and liabilities that are measured at fair value on a recurring basis and their carrying value (in millions):

			As of June 30, 2020
									Fair Value
			Carrying Value						Level 1						Level 2						Level 3
Cash and cash equivalents			$	641.9					$	641.9					$	—					$	—

			As of December 31, 2019
									Fair Value
			Carrying Value						Level 1						Level 2						Level 3
Cash and cash equivalents			$	487.4					$	487.4					$	—					$	—

Reconciliation of the Weighted Average Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The following table sets forth the reconciliation of the weighted average number of common shares used to compute basic and diluted net loss per share for the three and six months ended June 30, 2020 and 2019:

			Three Months Ended June 30,																		Six Months Ended June 30,
			2020						2019						2020						2019
			(in thousands, except per share amounts)
Numerator:
Net loss			$	(61,854)					$	(66,514)					$	(128,218)					$	(140,667)
Denominator:
Weighted average common shares used in calculation of basic net loss per share:			96,633						81,806						93,206						79,685
Effect of dilutive securities:
Common stock options			—						—						—						—
Restricted stock and RSUs			—						—						—						—
Convertible debt securities			—						—						—						—
Weighted average common shares outstanding used in calculation of diluted net loss per share			96,633						81,806						93,206						79,685
Net loss per share:
Basic and diluted			$	(0.64)					$	(0.81)					$	(1.38)					$	(1.77)

Potentially Dilutive Securities Excluded from Computations of Diluted Weighted Average Common Shares Outstanding

The following potentially dilutive securities have been excluded from the computations of diluted weighted average common shares outstanding as of June 30, 2020 and 2019 as their effect would have been anti-dilutive (in thousands):

			As of June 30,
			2020						2019
Common stock options			13,272						11,034
Unvested restricted stock and RSUs			868						475
Convertible debt securities			11,492						11,492

Schedules of Concentration of Risk, by Risk Factor

The following table presents the percentage of gross product revenue represented by the Company's three largest customers as of the six months ended June 30, 2020 and June 30, 2019.

			Percentage of Total Gross Product Revenue
			June 30, 2020						June 30, 2019
			Customer A			28%						31%
Customer B			26%						18%
Customer C			24%						30%

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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