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Consolidated Statements of Comprehensive Loss (unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Statement of Comprehensive Income [Abstract]
Revenues, net	$ 42,495	$ 29,972	$ 79,355	$ 51,874
Cost of product revenues (excluding amortization of intangible assets)	9,950	4,919	18,388	9,069
Gross profit	32,545	25,053	60,967	42,805
Operating expenses:
Research and development	35,748	33,538	71,932	64,741
Selling, general and administrative	49,663	52,433	101,009	107,243
Amortization of intangible assets	1,248	1,248	2,497	2,496
Total costs and expenses	86,659	87,219	175,438	174,480
Operating loss	(54,114)	(62,166)	(114,471)	(131,675)
Investment income	203	2,578	1,607	4,994
Interest expense	(7,469)	(6,785)	(14,880)	(13,511)
Other expense, net	(46)	(51)	(10)	(170)
Loss before income taxes	(61,426)	(66,424)	(127,754)	(140,362)
Provision for income taxes	428	90	464	305
Net loss	$ (61,854)	$ (66,514)	$ (128,218)	$ (140,667)
Basic and diluted net loss per share (in dollars per share)	$ (0.64)	$ (0.81)	$ (1.38)	$ (1.77)
Weighted average basic and diluted common shares outstanding (in shares)	96,633	81,806	93,206	79,685
Net loss	$ (61,854)	$ (66,514)	$ (128,218)	$ (140,667)
Other comprehensive income (loss):
Foreign currency translation (losses) gains	(51)	(37)	(88)	2
Total comprehensive loss	$ (61,905)	$ (66,551)	$ (128,306)	$ (140,665)

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